Featured Publications
Smartphone-Based Machine Learning Model for Real-Time Assessment of Medical… Smartphone-Based Machine Learning Model for…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue,…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue, based on the amount of cortex. The model was developed on smartphone images of 747 kidney biopsy cores from deceased donor kidneys,…
Cure Glomerulonephropathy Pathology Classification and Core Scoring Criteria,… Cure Glomerulonephropathy Pathology Classification…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD),…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy. We developed a conventional,…
Clinical and Histopathologic Characteristics of Pediatric Patients With Primary… Clinical and Histopathologic Characteristics of…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In recent years, several novel antigens have been implicated in the pathogenesis of PMN. However, the…
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(501 Results)
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Common Genetic Variants In The CLDN2 And PRSS1-PRSS2 Loci Alter Risk For Alcohol-Related And Sporadic Pancreatitis
Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic…
Read on PubMed• December 2012
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Determination Of Primary Versus Secondary Membranous Glomerulopathy Utilizing Phospholipase A2 Receptor Staining In Renal Biopsies
Autoantibody formation directed against phospholipase A2 receptor (PLA2R)1 is the underlying etiology in most cases of primary membranous glomerulopathy.
Read on PubMed• November 2012
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Primary Amebic Meningoencephalitis Deaths Associated With Sinus Irrigation Using Contaminated Tap Water
Naegleria fowleri is a climate-sensitive, thermophilic ameba found in the environment, including warm, freshwater lakes and rivers.
Read on PubMed• November 2012
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2,8-Dihydroxyadeninuria Disease
An 80-year-old Caucasian male was evaluated for delayed graft function (DGF) following renal transplantation.
Read on Kidney International• November 2012
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Renal Medullary Angiitis: A Case Series From A Single Institution
Renal medullary angiitis is a lesion involving the vasa recta of the medulla
Read on PubMed• October 2012
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Comprehensive Search For Alzheimer Disease Susceptibility Loci In The APOE Region
To evaluate the association of risk and age at onset (AAO) of Alzheimer disease (AD) with single-nucleotide polymorphisms (SNPs) in…
Read on PubMed• October 2012
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Male Microchimerism In The Human Female Brain
In humans, naturally acquired microchimerism has been observed in many tissues and organs. Fetal microchimerism, however, has not been investigated…
Read on PubMed• September 2012
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Metabolic Regulation Of Organelle Homeostasis In Lupus T Cells
Abnormal T-cell signaling and activation are characteristic features in systemic lupus erythematosus (SLE). Lupus T cells are shifted toward an…
Read on PubMed• September 2012
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N-Acetylcysteine Reduces Disease Activity By Blocking Mammalian Target Of Rapamycin In T Cells From Systemic Lupus Erythematosus Patients: A Randomized, Double-Blind, Placebo-Controlled Trial
Systemic lupus erythematosus (SLE) patients exhibit T cell dysfunction, which can be regulated through mitochondrial transmembrane potential (Δψm) and mammalian…
Read on PubMed• September 2012
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Case Report: Eculizumab Rescue Of Severe Accelerated Antibody-Mediated Rejection After Abo-Incompatible Kidney Transplant
ABO-incompatible (ABOI) living donor kidney transplantation has become a well-accepted practice with standard protocols using perioperative antibody-depleting therapies to lower…
Read on PubMed• September 2012
