Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.

All Publications
(480 Results)
-
Prenatal Stress Alters Progestogens To Mediate Susceptibility To Sex-Typical, Stress-Sensitive Disorders, Such As Drug Abuse: A Review
Maternal-offspring interactions begin prior to birth. Experiences of the mother during gestation play a powerful role in determining the developmental…
Read on PubMed• October 2011
-
Association Of Common Variants In The Human Eyes Shut Ortholog (EYS) With Statin-Induced Myopathy: Evidence For Additional Functions Of EYS
Of the nearly 38 million people in the USA who receive statin therapy, 0.1-0.5% experience severe or life-threatening myopathic side…
Read on PubMed• October 2011
-
Alzheimer Disease Pathology In Subjects Without Dementia In 2 Studies Of Aging: The Nun Study And The Adult Changes In Thought Study
Individuals with antemortem preservation of cognition who show autopsy evidence of at least moderate Alzheimer disease (AD) pathology suggest the…
Read on PubMed• October 2011
-
Role Of Cerebrospinal Fluid And Plasma Biomarkers In The Diagnosis Of Neurodegenerative Disorders And Mild Cognitive Impairment
Biomarkers are one type of laboratory testing being developed in response to the therapeutic imperative for diseases that cause cognitive…
Read on PubMed• October 2011
-
White Matter Lesions Defined By Diffusion Tensor Imaging In Older Adults
The cellular and molecular mechanisms underlying magnetic resonance imaging-defined white matter (WM) changes associated with age-related cognitive decline remain poorly…
Read on PubMed• September 2011
-
Ecology Of The Aging Human Brain
Alzheimer disease, cerebral vascular brain injury, and isocortical Lewy body disease (LBD) are the major contributors to dementia in community-…
Read on PubMed• August 2011
-
Novel Late-Onset Alzheimer Disease Loci Variants Associate With Brain Gene Expression
Recent genome-wide association studies (GWAS) of late-onset Alzheimer disease (LOAD) identified 9 novel risk loci. Discovery of functional variants within…
Read on PubMed• July 2011
-
Cognitive Activities During Adulthood Are More Important Than Education In Building Reserve
Cognitive reserve is thought to reflect life experiences. Which experiences contribute to reserve and their relative importance is not understood.…
Read on PubMed• July 2011
-
Neuropathological Associates Of Multiple Cognitive Functions In Two Community-Based Cohorts Of Older Adults
Studies of neuropathology-cognition associations are not common and have been limited by small sample sizes, long intervals between autopsy and…
Read on PubMed• July 2011
-
Diagnosis Of IgG4-Related Tubulointerstitial Nephritis
IgG4-related systemic disease is an autoimmune disease that was first recognized in the pancreas but also affects other organs.
Read on PubMed• June 2011
