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Vasculitic Myopathy

Jon Wilson, MD neuropathologist at arkana laboratories
By Jon Wilson, MD

Aug 26, 2022

vasculitis (“vasculitic myopathy”)

This 50-year-old patient presented with fever and bilateral leg myalgias. Laboratory studies showed elevated ESR (120) and normal CPK. On physical examination the patient was noted to have pain upon palpation from the posterior knee down to the calf muscles on both sides.


What is your pathologic diagnosis?

A. Trichinellosis

B. Vasculitis

C. Sarcoidosis

D. Polymyositis



Answer: Vasculitis

The morphologic alterations are consistent with the pathologic diagnosis of vasculitis (“vasculitic myopathy”).


Reference(s) / additional reading:

Marcus ViniciusPinto, Kenneth Warrington, Matthew Koster, ElieNaddaf. Myopathy: an underrecognized manifestation of vasculitis (2864).  Neurology 2020, 94 (15 Supplement) 2864


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