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PAS-pale, focally fractured tubular casts with associated cellular reaction
Teaching Points

Light Chain Cast Nephropathy with Congo Red Staining

This biopsy was taken from a 60-year-old African American female with a history of diabetes mellitus and hypertension, who presented…

Amyloid Cast Nephropathy
Teaching Points

Amyloid Cast Nephropathy

Cases of light chain cast nephropathy occasionally show amyloid staining properties including positive staining for Congo red with green birefringence…

Amyloid Casts
Teaching Points

Amyloid Casts

The differential diagnosis of acute renal failure in patients with multiple myeloma includes light chain cast nephropathy, amyloidosis, and monoclonal…