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Hybrid myofibers
Clinical History: This previously healthy 35-year-old patient presented with proximal upper and lower extremity weakness and myalgias. Laboratory studies showed…
Freezing artifact formalin-fixed tissue
Clinical History: This 50-year-old patient presented with generalized muscle weakness and elevated CPK levels. Muscle biopsy was performed to evaluate…
Extrafusal and Intrafusal Fibers
Clinical History This 1-year-old patient underwent muscle biopsy to evaluate for hypotonia. What are the muscle fibers within the small…
Signet Ring Carcinoma
Clinical History This 50-year-old patient presented with muscle weakness and stiffness. They had recently been identified to have diffuse thickening…
Arterioles, Venules, and Lymphatics
Clinical HistoryThis 50-year-old patient presented with right thigh pain. Their muscle biopsy showed mild denervation type changes. Several small portions…
Myopathy in Acute Lymphoma
Clinical HistoryThis 77-year-old patient presented with atrophy of the cranial and extremity muscles, dysphagia, and multiple falls. Past medical history…