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Thrombotic Microangiopathy
Art of Medicine

Art of Medicine: Thrombotic Microangiopathy

The above painting shows a glomerulus containing capillary loop fibrin thrombi, an arteriole with onion-skinning, and acute tubular injury, findings…

atypical hemolytic-uremic syndrome, arkana laboratories, renal pathology
KDIGO Connections

KDIGO Connections: Atypical Hemolytic-Uremic Syndrome

How do you treat patients with atypical hemolytic-uremic syndrome?    

Antiphospholipid Antibody Syndrome
Teaching Points

Antiphospholipid Antibody Syndrome

This biopsy shows glomerular arteriolar and capillary thrombi characteristic of thrombotic microangiopathy (TMA). Immunofluorescence studies (not shown) are negative for…


Thrombotic Microangiopathy
Teaching Points

Thrombotic Microangiopathy

The image (trichrome stain) shows the characteristic arteriolar lesion of acute thrombotic microangiopathy. Note the prominent mucoid intimal edema and…

Postpartum Hemolytic Uremic Syndrome (HUS)
Teaching Points

Postpartum HUS

This 22-year-old Caucasian female presented with acute renal failure and proteinuria five days after delivering her first child. The pregnancy…