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Art of Medicine
Art of Medicine: Thrombotic Microangiopathy
The above painting shows a glomerulus containing capillary loop fibrin thrombi, an arteriole with onion-skinning, and acute tubular injury, findings…
KDIGO Connections
KDIGO Connections: Atypical Hemolytic-Uremic Syndrome
How do you treat patients with atypical hemolytic-uremic syndrome?
Teaching Points
Antiphospholipid Antibody Syndrome
This biopsy shows glomerular arteriolar and capillary thrombi characteristic of thrombotic microangiopathy (TMA). Immunofluorescence studies (not shown) are negative for…
Teaching Points
Thrombotic Microangiopathy
The image (trichrome stain) shows the characteristic arteriolar lesion of acute thrombotic microangiopathy. Note the prominent mucoid intimal edema and…
Teaching Points
Postpartum HUS
This 22-year-old Caucasian female presented with acute renal failure and proteinuria five days after delivering her first child. The pregnancy…
