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Dual Diagnosis Of Histiocytoid Sweet Syndrome And Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Histiocytoid Sweet syndrome (H-SS) is a rare variant of acute febrile neutrophilic dermatosis. It isfrequently associated with hematologic malignancies but…
Collapsing Glomerulopathy In A Patient With Mixed Connective Tissue Disease
Collapsing glomerulopathy (CG) is a form of podocytopathy that is challenging to manage. CG can be idiopathic or associated with…
High-Speed Light-Sheet Microscopy For The In-Situ Acquisition Of Volumetric Histological Images Of Living Tissue
Histological examinations typically require the excision of tissue, followed by its fixation, slicing, staining, mounting and imaging, with timeframes ranging…
Ext1 And Ncam1-Associated Membranous Lupus Nephritis In A Cohort Of Patients Undergoing Repeat Kidney Biopsies
EXT1/2 and NCAM1 associated membranous lupus nephritis (MLN) may represent distinct disease phenotypes with prognostic significance.
Cell Type-Specific Mechanistic Target Of Rapamycin-Dependent Distortion Of Autophagy Pathways In Lupus Nephritis
Pro-inflammatory immune system development, metabolomic defects, and deregulation of autophagy play interconnected roles in driving the pathogenesis of systemic lupus…
Cubilin And Amnionless Protein Are Novel Target Antigens in Anti–Brush Border Antibody Disease
The kidney proximal tubule reabsorbs large amounts of low-molecular-weight proteins, albumin, electrolytes, and solutes from the glomerular filtrate to the…
Antibody-Suppressor Cxcr5 + Cd8 + T Cellular Therapy Ameliorates Antibody-Mediated Rejection Following Kidney Transplant In Ccr5 Ko Mice
CCR5 KO kidney transplant (KTx) recipients are extraordinarily high alloantibody producers and develop pathology that mimics human antibody-mediated rejection (AMR).
Lipoic Acid In Neural Epidermal Growth Factor-Like 1-Associated Membranous Nephropathy: More Than A Coincidence?
We found the study by Spainetal., Lipoic Acid Supplementation Associated With Neural Epidermal Growth Factor-Like 1 (NELL1)Associated Membranous Nephropathy, to…
Increasing Incidence Of Inadequate Kidney Biopsy Samples Over Time: A 16-Year Retrospective Analysis From A Large National Renal Biopsy Laboratory
Recently, there has been a perceived change in the number of inadequate samples. The aim of this study was to…
Abi1-Based Expression Signature Predicts Breast Cancer Metastasis And Survival
Despite the current standard of care, breast cancer remains one of the leading causes of mortality in women worldwide, thus…
Use Of A Smartphone Camera At The Bedside To Assess Adequacy Of Kidney Biopsies
Kidney biopsies are the gold standard for diagnosis in evaluating native and transplanted kidney disorders. Obtaining adequate tissue samples is…
Development And External Validation Of A Diagnostic Model For Biopsy-Proven Acute Interstitial Nephritis Using Electronic Health Record Data
Patients with acute interstitial nephritis (AIN) can present without typical clinical features, leading to a delay in diagnosis and treatment.…
How Times Have Changed! A Cornucopia Of Antigens For Membranous Nephropathy
The identification of the major target antigen phospholipase A2 receptor (PLA2R) in the majority of primary (idiopathic) cases of membranous…
Arcane Apoptosis In Appendicitis: Clue To Covid-19 In Children Or Coincidence?
We had observed increased apoptosis in two appendixes in children who developed acute appendicitis after COVID-19 infection. We wondered if…
The Characteristics Of Patients With Kidney Light Chain Deposition Disease Concurrent With Light Chain Amyloidosis
The type of monoclonal light chain nephropathy is thought to be largely a function of the structural and physiochemical properties…