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April 2, 2021
Twitter Poll (April 1, 2021)

- Published: April 2, 2021
- By: Joel Murphy, MD
Answer: Granulomatous TIN
The classic finding for renal sarcoidosis is that of a non-necrotizing granulomatous tubulointerstitial nephritis (Granulomatous TIN). However, on biopsy this finding is non-specific and thus the differential diagnosis would also include drug/hypersensitivity reaction, infections (i.e. mycobacterial, fungal), and autoimmune disease. Sarcoidosis is considered a diagnosis of exclusion and thus clinical correlation is required.