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Twitter Poll (February 20, 2019)

Vanessa Moreno, MD
By Vanessa Moreno, MD

Feb 21, 2019

Antibody-Mediated Rejection, Twitter Poll, Arkana Laboratories

ANSWER: B

The findings are suspicious for active antibody-mediated rejection (ABMR), based on the presence of moderate glomerulitis (g2), severe peritubular capillaritis (ptc3) and C4d staining in PTCs (C4d2). Serologic evidence of DSA is advised in order to meet the criteria for diagnosis.

Reference:

Haas M, et al. The Banff 2017 Kidney Meeting Report: Revised diagnostic criteria for chronic active T-cell mediated rejection, antibody-mediated rejection, and prospects for integrative endpoints for next-generation clinical trials. Am J Transplant. 2018; 1-15.

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