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ABMR ALECT2 Fibrillary Glomerulopathy
Banff and Beyond

ABMR, ALECT, and Fibrillary Glomerulopathy

Welcome back to another interesting case in our Banff and Beyond series. To begin, the history is a 59 y/o…

Banff and Beyond Intro Graphic
Banff and Beyond

Utilizing the Banff Guidelines

Welcome to our new transplant series, Banff and Beyond! Throughout this series, Dr. Murphy will provide short, concise examples of…

Diagnose This!

Diagnose This (January 3, 2022)

In a renal allograft biopsy with this finding, what is your diagnosis? …


antibody-mediated rejection, arkana laboratories, renal pathology, diagnose this, kidney disease
Diagnose This!

Diagnose This (January 12, 2021)

What are the two major changes seen in this image from an allograft kidney and what are these findings concerning…

mesangiolysis, renal pathology, kidney biopsy stain, arkana laboratories
Diagnose This!

Diagnose This (August 5, 2019)

What is this finding in this native kidney? …

By L. Nich Cossey, MD
Antibody-Mediated Rejection, Twitter Poll, Arkana Laboratories
Twitter Poll

Twitter Poll (February 20, 2019)

ANSWER: B The findings are suspicious for active antibody-mediated rejection (ABMR), based on the presence of moderate glomerulitis (g2), severe…

By Vanessa Moreno, MD

Acute Tissue Injury
Twitter Poll

Twitter Poll (May 23, 2018)

True! Histologic evidence of acute tissue injury in AABMR includes 1 or more of the following: microvascular inflammation (glomerulitis and/or…

By Vanessa Moreno, MD
transplant glomerulopathy, Chronic Active Antibody-Mediated Rejection
Teaching Points

Chronic Active Antibody-Mediated Rejection

A diagnosis of chronic active antibody-mediated rejection (ABMR) requires morphologic evidence of chronic tissue injury (e.g. transplant glomerulopathy), evidence of…

Transplant Arteriopathy, active antibody-mediated rejection
Diagnose This!

Diagnose This! (March 19, 2018)

What is your diagnosis in this renal transplant biopsy? …

By L. Nich Cossey, MD

Intimal Arteritis
Twitter Poll

Twitter Poll (Febuary 28, 2018)

ANSWER: C Intimal arteritis (v1 and v2) is more commonly associated with mixed ABMR/TCMR than with pure ABMR. It may…

By Vanessa Moreno, MD
Active Antibody Mediated Rejection
Diagnose This!

Diagnose This! (February 19, 2018)

What is your diagnosis in this renal transplant patient?   …

By L. Nich Cossey, MD
acute antibody-mediated rejection
Pushing Glass

Pushing Glass (October 10, 2017)

The patient is a 50-year-old African-American female with a past medical history significant for ESRD secondary to lupus nephritis who…


chronic transplant arteriopathy
Teaching Points

Chronic Transplant Arteriopathy

This image shows an arterial cross-section with features of chronic transplant arteriopathy (a.k.a. sclerosing transplant vasculopathy and chronic allograft vasculopathy).…

Glomerulitis
Teaching Points

Glomerulitis

This image (Jones silver stain) shows prominent glomerulitis in an allograft kidney biopsy, characterized in this case by increased mononuclear…

intimal arteritis
Diagnose This!

Diagnose This! (August 28, 2017)

What is this finding and what is the most likely etiology?   …

By L. Nich Cossey, MD