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Twitter Poll (May 27, 2021)
Answer: D, PAS-positive
The typical histologic features of casts seen in cases of light chain cast nephropathy show light chain restriction by immunofluorescence, are typically PAS-weak or negative in their staining, show fracturing, and will classically show an associated intratubular cellular reaction. Typically these casts will involve the distal tubules and collecting ducts and occasionally, crystal formation can occur.
Quick note: This post is to be used for informational purposes only and does not constitute medical or health advice. Each person should consult their own doctor with respect to matters referenced. Arkana Laboratories assumes no liability for actions taken in reliance upon the information contained herein.