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November 28, 2018

Arteriole Transition

The image captures the transition of an arteriole as it loses its internal elastic lamina (black arrow).  Note that the smaller arteriole branch, while lacking this elastic layer, still retains smooth muscle cells (red arrow).  The elastic tissue adds structural integrity to arterial and larger arteriolar walls during pulsatile distension from higher intravascular pressure, and the retained muscular layer in small arterioles helps provide an important component of the pre-capillary sphincter mechanism, whereby regulation of blood flow to capillary beds occurs.