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Hepatic Glomerulosclerosis
Diagnose This!

Diagnose This! (January 9, 2023)

This is the biopsy of a 45 yo with alcoholic cirrhosis, bacteremia, hematuria, proteinuria and AKI. IF shows IgA (3+),…

The biopsy shows glomerular capillary wall double contouring, segmental glomerular microaneurisms and hyalinosis. These findings are typical of anti-VEGF therapy-induced glomerular microangiopathy.
Diagnose This!

Diagnose This (October 10, 2022)

This is the biopsy of a 47-year-old female with cervical cancer, on anti-VEGF therapy, with proteinuria and normal renal function.…

Diagnose This!

Diagnose This (September 26, 2022)

This is the biopsy from a 73-year-old with AKI and normal bone marrow biopsy done for investigation of anemia and…

NPHP1-related nephronophthisis
Diagnose This!

Diagnose This (September 19, 2022)

In a 26-year-old obese Black female with no significant PMH and elevated creatinine, what is your top diagnosis?    …

Diagnose This!

Diagnose This (August 29, 2022)

In a patient with progressively rising serum creatinine and a history of CABG 2 months prior, what is your diagnosis?…

Thrombotic microangiopathy
Diagnose This!

Diagnose This (August 22, 2022)

This is a 3 month post-transplant kidney biopsy from a patient with ESRD due to polycystic kidney disease. She recently…

H&E stain showing numerous hematoxylin bodies
Diagnose This!

Diagnose This (August 15, 2022)

What is this finding and what is the diagnosis?     This is an H&E stain showing numerous hematoxylin bodies.…

chronic antibody mediated rejection, peritubular capillary basement membrane multilayering
Diagnose This!

Diagnose This (August 8, 2022)

In a renal allograft, what is your diagnosis given these ultrastructural findings?   The EM picture shows glomerular basement membrane…

class IV lupus nephritis on IF stain
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Diagnose This (August 2, 2022)

These are the C1q and C3 stains of the biopsy of a 13-year-old female with hematuria and proteinuria. Given these…

toluidine blue section showing fabry disease
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Diagnose This (July 25, 2022)

What is your diagnosis?   This is a toluidine blue section showing numerous densely stained lipid inclusions in podocytes, some…

Membranous Nephropathy
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Diagnose This (July 4, 2022)

This is the C4d immunofluorescence from a 5 year post-transplant biopsy of an AA female who had ESRD due to…

Endocapillary Hypercellularity B
Diagnose This!

Daignose This (June 27, 2022)

In a patient who is an IV drug user and IF showing C3 only staining, what is your diagnosis? The…

Cholesterol Arterial Emboli
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Diagnose This (April 25, 2022)

This is an IgG IF viewed under both fluorescent and polarized light from a patient with AKI following endovascular procedure.…

cmv pneumonia
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Diagnose This (April 18, 2022)

This 32-year-old renal transplant recipient had AKI and pneumonia. A recent biopsy had shown borderline changes for TCMR and the…

Diagnose This!

Diagnose This (April 4, 2022)

This is the biopsy of a 62yo Hispanic female with hematuria and proteinuria. What is this stain and what is…