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Diagnose This 4/29/2024
What would be your leading Dx and subtype based on the Congo red image above showing deposition predominately in the…
![](https://www.arkanalabs.com/wp-content/uploads/2024/04/4.15-Dx--432x288.jpg)
Diagnose This 4/15/2024
Based on the image provided, what would be your leading diagnosis with C3-dominant immune-complex deposition? The light microscopic image depicts…
![](https://www.arkanalabs.com/wp-content/uploads/2024/04/Dx-This-4.1.24-1-432x288.png)
Diagnose This 4/1/2024
What is this finding and what is the significance in the transplant setting? The light microscopic image depicts an…
![](https://www.arkanalabs.com/wp-content/uploads/2024/03/dx-this-3.18-432x288.png)
Diagnose This 3/18/2024
What is at the top of your differential in a patient with a positive SPEP (IgG kappa) and the immunofluorescence…
![](https://www.arkanalabs.com/wp-content/uploads/2024/03/Dx-this-3.11-1-432x288.png)
Diagnose This 3/11/2024
What is your diagnosis in a patient with nephrotic syndrome? The electron photomicrograph demonstrates frequent subepithelial deposits along the glomerular…
![](https://www.arkanalabs.com/wp-content/uploads/2024/03/alport-syndrome-3.4-432x288.png)
Diagnose This 3/4/2024
The ultrastructural abnormalities present in the image are suspicious for what underlying disease? The electron photomicrograph demonstrates two abnormal…
![](https://www.arkanalabs.com/wp-content/uploads/2024/02/Dx-This-2.26-1-432x288.png)
Diagnose This 2/26/2024
What is your diagnosis based on the EM image provided? The electron microscopy image provided is that of portions of…
![](https://www.arkanalabs.com/wp-content/uploads/2024/02/Dx-this-2.19.24-1-432x288.png)
Diagnose This 2/19/2024
What is your leading diagnosis when seeing this particular IgG staining pattern? Answer: Fibrillary Glomerulopathy The immunofluorescence shows…
![](https://www.arkanalabs.com/wp-content/uploads/2024/02/Dx-this-2.12.24-1-432x288.png)
Diagnose This 2/12/2024
What is your diagnosis? The light microscopic image depicts a renal transplant biopsy with multiple histiocytes containing intracytoplasmic, targetoid…
![](https://www.arkanalabs.com/wp-content/uploads/2024/02/chronic-active-ABMR-2.5.2024-432x288.png)
Diagnose This 2/5/2024
What is your diagnosis in this transplant biopsy given the features present? Answer: Chronic active antibody-mediated rejection The features…
![](https://www.arkanalabs.com/wp-content/uploads/2024/01/Dx-This-1.29.24-Copy-1-432x288.png)
Diagnose This 1/29/2024
What stain would you order to clinch the diagnosis in this transplant patient with AKI? A CMV stain is…
![](https://www.arkanalabs.com/wp-content/uploads/2024/01/Diagnosis-This-1152024-432x288.png)
Diagnosis This 1/15/2024
What considerations should be included in your differential diagnosis given the provided histologic finding? The image of a Jones silver…
![Hepatic Glomerulosclerosis](https://www.arkanalabs.com/wp-content/uploads/2023/01/22429-22-CNEM_003-432x288.jpg)
Diagnose This! (January 9, 2023)
This is the biopsy of a 45 yo with alcoholic cirrhosis, bacteremia, hematuria, proteinuria and AKI. IF shows IgA (3+),…
![The biopsy shows glomerular capillary wall double contouring, segmental glomerular microaneurisms and hyalinosis. These findings are typical of anti-VEGF therapy-induced glomerular microangiopathy.](https://www.arkanalabs.com/wp-content/uploads/2022/10/Dx-this-without-logo-432x288.png)
Diagnose This (October 10, 2022)
This is the biopsy of a 47-year-old female with cervical cancer, on anti-VEGF therapy, with proteinuria and normal renal function.…
![](https://www.arkanalabs.com/wp-content/uploads/2022/09/Capillary-loops-with-large-atypical-cells-432x288.png)
Diagnose This (September 26, 2022)
This is the biopsy from a 73-year-old with AKI and normal bone marrow biopsy done for investigation of anemia and…