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Art of Medicine
Art of Medicine: Anti-Brush Border Antibody Disease
The above painting shows massive tubular basement membrane (electron dense on EM) deposits along proximal tubules with sparing of the…
Twitter Poll
Twitter Poll (January 16, 2019)
ANSWER: B The target of the circulating ABBA autoantibodies is LDL receptor-related protein 2 (LRP2) also known as Megalin. ABBA…
Teaching Points
Anti-Brush Border Antibody Disease
Anti-LRP2 nephropathy is a form of kidney disease primarily affecting the elderly in which progressive renal tubular injury is seen…
Teaching Points
Anti-Brush Border Antibody Disease IF
These photomicrographs show the classic immunofluorescence staining pattern for anti-LRP2 nephropathy, a disease that leads to severe renal tubular injury…
Diagnose This!
Diagnose This! (February 13, 2017)
Please pick the best answer. These images show characteristic findings of which of the following diseases: A) IgG4-Related Disease B)…
