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Lymphocytes
Clinical History:Patient presented with progressive proximal weakness since August and severe x2 weeks.Past medical history: hyperthyroidism, hyperlipidemia, herpes simplex, hypertension.Medications:…
Rhabdomyolysis
Clinical historyThis 20-year-old patient was found in a prolonged seizure state (status epilepticus of unknown duration). CPK levels at the…
Myofiber Injury
Clinical HistoryThe 50-year-old patient presented with proximal upper and lower extremity muscle weakness of several months duration. They also related…
Necrotic Myofibers
This 20-year-old patient presented with acute onset muscle weakness and numbness. Laboratory studies showed elevated CPK (4000) and negative toxin/drug…
Myalgias After Eating Fish
This 35-year-old previously healthy patient developed generalized myalgias, muscle weakness, and dark colored urine the day after eating cooked fish…
Lipid Storage Myopathy
This adult patient presented with progressive muscle weakness, elevated CK, and was admitted for rhabdomyolysis. Skeletal muscle biopsy was performed…
Diagnose This (November 19, 2018)
What is your diagnosis? What additional stains would you like to confirm your diagnosis? …
A source of myoglobinuria…
The image shows a frozen cross section of skeletal muscle from a patient with rhabdomyolysis, which included the full clinical…
Twitter Poll (January 24, 2018)
ANSWER: CPatients with rhabdomyolysis present with acute tubular injury with pigmented casts (myoglobin casts) positive for myoglobin
Myoglobin Casts
A 54-year-old man with a history of hypertension and hypercholesterolemia presented with complaints of generalized “muscle stiffness” and cola-colored urine.…