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Neuro Notes

Necrotic Myofibers

This 20-year-old patient presented with acute onset muscle weakness and numbness. Laboratory studies showed elevated CPK (4000) and negative toxin/drug…

Toxic Myopathy Due to Ingestion of Palytoxin, Low magnification image showing frequent scattered pale staining muscle fibers which have lost their nuclear staining for hematoxylin
Neuro Notes

Myalgias After Eating Fish

This 35-year-old previously healthy patient developed generalized myalgias, muscle weakness, and dark colored urine the day after eating cooked fish…

Lipid Storage Myopathy, Arkana Laboratories, neuro notes, neuropathology, molecular pathology
Neuro Notes

Lipid Storage Myopathy

This adult patient presented with progressive muscle weakness, elevated CK, and was admitted for rhabdomyolysis. Skeletal muscle biopsy was performed…

By Kelly Mrachek, MD

Rhabdomyolysis in kidney biopsy at Arkana Laboratories
Diagnose This!

Diagnose This (November 19, 2018)

What is your diagnosis? What additional stains would you like to confirm your diagnosis? …

By L. Nich Cossey, MD
Teaching Points

A source of myoglobinuria…

The image shows a frozen cross section of skeletal muscle from a patient with rhabdomyolysis, which included the full clinical…

Twitter Poll

Twitter Poll (January 24, 2018)

ANSWER: C Patients with rhabdomyolysis present with acute tubular injury with pigmented casts (myoglobin casts) positive for myoglobin

By Vanessa Moreno, MD

Diagnose This!

Diagnose This! (July 24, 2017)

What is your diagnosis?     …

By L. Nich Cossey, MD
acute tubular injury with numerous pigmented myoglobin casts
Teaching Points

Myoglobin Casts

A 54-year-old man with a history of hypertension and hypercholesterolemia presented with complaints of generalized muscle stiffness and cola-colored urine.…