What’s your diagnosis?
This photomicrograph shows granular, capillary wall staining by IgG as well as a tissue ANA pattern. These findings are suspicious for a membranous lupus nephritis, ISN/RPS Class V which was confirmed by full-house immunofluorescence staining (not shown), subepithelial and intramembranous immune complex deposits on electron microscopy (not shown) and the patient’s clinical history of systemic lupus erythematosus.
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