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Focal and Segmental Glomerulosclerosis
Diagnose This!

Diagnose This (February 7, 2022)

In a patient with subnephrotic proteinuria, negative immunofluorescence, and segmental foot process effacement, what is your diagnosis? …

What is Chronic Kidney Disease, Kidney Biopsy, Kidneys and How They Work, Diabetes Mellitus, Hypertension, Kidneys for Kids, ALect2, IgA Nephropathy, Membranous GlomerulopathyMembranous Glomerulopathy, Focal Segmental Glomerulosclerosis
Patient Resources

Membranous Glomerulopathy

What is membranous glomerulopathy? Membranous glomerulopathyis a kidney disease that causes protein in the urine (proteinuria). In membranous glomerulopathy, immune…

Amyloidosis, AA amyloid, IV drug, proteinuria
Diagnose This!

Diagnose This (August 24, 2021)

This is the biopsy of a 32yo IV drug user who has nephrotic range proteinuria and MSSA bacteremia secondary to…


MGMID
Disease Week

Disease Week: MGMID

Tuesday: Let’s start with a poll. You have a 25-year-old female patient with a positive ANA and proteinuria. On a…

Scanning EM of a Proteinuric Glomerulus, eyescandy, renal pathology, arkana laboratories
eyeSCANdy

Scanning EM of a Proteinuric Glomerulus

This eyeSCANdy image shows scanning EM of a proteinuric glomerulus with capillary loop showing widening and partial loss of interdigitating…

glomerulomegaly, arkana laboratories, renal pathology, diagnose this, kidney pathology
Diagnose This!

Diagnose This (November 16, 2020)

  What conditions would be in your differential diagnosis for this finding? (Hint: large glomerulus)   …


Alport Syndrome, Arkana Laboratories, diagnose this, renal pathology, kindey path, kidney disease
Diagnose This!

Diagnose This (November 2, 2020)

What is this finding? In a young male patient with hematuria and hearing loss, what would be your top diagnosis?…

Fibrillary glomerulonephritis, arkana laboratories, twitter poll
Twitter Poll

Twitter Poll (September 16, 2020)

Answer: C Fibrillary glomerulonephritis is a rare disease affecting less than 1% of all native kidney biopsies and is due…

Membranous Lupus Nephritis, arkana laboratories, renal pathology, kidney biopsy
Teaching Points

Membranous Lupus Nephritis

The patient is a 19-year-old female who presents with hematuria, nephrotic range proteinuria, and a creatinine of 1.2 mg/dL. She…

Michael Kuperman, MD renal pathologist at arkana laboratories
By Michael Kuperman, MD

Collapsing Glomerulopathy
Art of Medicine

Art of Medicine: Collapsing Glomerulopathy

The above painting shows a glomerulus with capillary tuft collapse, visceral epithelial cell hyperplasia, and numerous protein resorption droplets within…

Diabetic Nephropathy, Art of Medicine
Art of Medicine

Art of Medicine: Diabetic Nephropathy

The above painting shows glomeruli with nodular mesangial expansion and arterial hyalinosis, changes frequently seen in diabetic nephropathy. Diabetic nephropathy…

KDIGO Connections

KDIGO Connections: Membranous Diagnosis Algorithm

Have you seen the latest proposed KDIGO algorithm for the diagnosis and treatment of membranous glomerulopathy? Dr. Bourne brings us…


KDIGO Connections

KDIGO Connections: HCV-Associated Kidney Disease

How do you treat patients with hepatitis C-associated kidney disease?

IgA nephropathy, Twitter Poll, Arkana Laboratories, kidney pathology, renal disease
Twitter Poll

Twitter Poll (May 22, 2019)

ANSWER: C By the Oxford Classification of IgA nephropathy, the findings present are classified as “M1 E1 S1 T1 C0”…

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What does minimal change disease look like?
Art of Medicine

Art of Medicine: Minimal Change Disease

The above painting shows podocytes with foot processes extending along the glomerular basement membrane of neighboring capillary loops. Effacement of…