Diagnose This (May 10, 2021)
What is your diagnosis for this finding in a young patient with renal artery stenosis?
This is an example of juxtaglomerular apparatus hyperplasia. Potential causes of juxtaglomerular apparatus hyperplasia include conditions that chronically stimulate renin production including Bartter and Gitelman syndromes, chronic renal ischemia, hypertrophy of the arterial and arteriolar walls, chronic volume depletion, Addison disease, renal artery stenosis, cardiac failure, and medications including calcineurin inhibitors, ACEIs or ARBs, and diuretics.
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