May 14, 2018
Diagnose This! (May 14, 2018)

- Published: May 14, 2018
- By: L. Nich Cossey, MD
- Tags: Acute interstitial nephritis, Acute kidney injury, Drug/hypersensitivity reaction, Eosinophils
What is your diagnosis?
The images show lymphocytic tubulitis as well as an eosinophil-rich interstitial inflammatory infiltrate. These findings are consistent with acute interstitial nephritis. The eosinophil-rich nature of the infiltrate is compatible with a drug/hypersensitivity reaction which was present in this patient, occurring from recent antibiotics exposure with subsequent acute renal failure and development of a rash.