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June 1, 2017
Fabry EM

- Published: June 1, 2017
- By: Chris Larsen, MD and Arkana Author
- Tags: Chronic kidney disease, Fabry disease, GLA, Myeloid bodies, Zebra bodies
Electron photomicrograph of a glomerular podocyte showing the characteristic electron dense laminated inclusions of Fabry disease. Fabry is a lysosomal storage disease with X-linked inheritance. Mutations in the gene for the enzyme alpha galactosidase A (GLA) result in accumulation of a glycolipid known as globotriaosylceramide (GL-3) in tissues including the kidney.