The association of rare autoimmune responses to vaccination is well known. This study investigates the effect of COVID-19 vaccination on the kidney. In a six-month period, 29 cases (including relapse of disease) were identified with temporal association to COVID-19 vaccination out of approximately 10,000 biopsies. The most common diagnoses were IgA Nephropathy (10 cases), minimal change disease (7 cases), and crescentic glomerulopathy with positive ANCA (6 cases). The overall frequency of these diseases was not increased compared to pre-pandemic levels. The true incidence and association with vaccination is not entirely clear in this period of mass vaccination. An NIH registry for glomerulonephritis post-COVID-19 vaccination has been created to further study this topic and is open to international patients. See the link below if you would like to register a patient.
Link to the registry (Glomerulonephritis post-COVID-19 vaccination): https://redcapsurvey.niddk.nih.gov/surveys/?s=LCDAMFD9JA
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