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Use of a Smartphone Camera at the Bedside to Access Adequacy of Kidney Biopsies
Over the past decade, there has been a dramatic increase in kidney biopsy inadequacy rate. Evaluation of biopsy adequacy by…
EXT1 And NCAM1-Associated Membranous Lupus Nephritis In A Cohort Of Patients Undergoing Repeat Kidney Biopsies
Systemic lupus erythematosus (SLE) is an autoimmune disease in which approximately 50% of patients have kidney involvement (lupus nephritis). Membranous…
How Times Have Changed! A Cornucopia of Antigens for Membranous Nephropathy
Membranous Nephropathy, or Membranous Glomerulopathy, is an autoimmune disease-causing nephrotic syndrome in which there is subepithelial deposition of IgG and…
Lipoic acid in neural epidermal growth factor-like 1-associated membranous nephropathy: More than a coincidence?
NELL1 is a recently described antigen seen in membranous glomerulopathy, which has been associated with malignancy. A recent study linked…
Increasing Incidence of Inadequate Kidney Biopsy Samples Over Time
A renal biopsy is an invasive procedure requiring sedation that is often necessary for appropriate patient treatment. A biopsy is…
Transforming Growth Factor Beta Receptor 3 (TGFBR3)-Associated Membranous Nephropathy
Approximately half of lupus patients have kidney disease, including membranous glomerulopathy. On renal biopsy, immunofluorescence shows granular capillary loop deposits,…
Glomerular Disease in Temporal Association to SARS-CoV-2 Vaccination – A Series of 29 Cases
The association of rare autoimmune responses to vaccination is well known. This study investigates the effect of COVID-19 vaccination on…
(NCAM1) Neural Cell Adhesion Molecule 1 Is A Novel Autoantigen In Membranous Lupus Nephritis
Membranous nephropathy is a leading cause of nephrotic syndrome. On renal biopsy, immunofluorescence shows granular capillary loop deposits, and holes…
NELL1 Is A Target Antigen In Malignancy-Associated Membranous Nephropathy
Membranous nephropathy is a leading cause of nephrotic syndrome. On renal biopsy, immunofluorescence shows granular capillary loop deposits, and holes…
Infantile Nephrocalcinosis Resulting From a Pathogenic CYP24A1 Mutation
Nephrocalcinosis is the finding of abundant calcium phosphate deposits within the tubulointerstitium of the kidney. This is a case report…
Resistant Starch Slows the Progression of CKD in the 5/6 Nephrectomy Mouse Model
In patients with chronic kidney disease, toxins normally excreted by the kidney continue to circulate, leading to increased kidney damage.…
A Diagnostician’s Field Guide To Crystalline Nephropathies
This discussion focuses on a review article of crystals seen in renal biopsies. Crystalline nephropathies are often associated with systemic…
A Practical Approach To The Pathology Of Renal Intratubular Casts
Dr. May discusses a review article with Dr. Dvanajsack that focuses on renal intratubular casts in Episode 5 of Arkana…
Viral-like Inclusions in COVID-19 Negative Renal Biopsies by Electron Microscopy
In Episode 4 of Arkana Advances, Dr. May interviews Dr. Cassol over her recent publication discussing viral-like inclusions in COVID-19…
Collapsing Glomerulopathy and APOL1 High-Risk Genotype Associated with Covid-19
Dr. May and Dr. Larsen discuss Covid-19 and its effect on collapsing glomerulopathy and APOL1 in Episode 3 of Arkana…