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How Times Have Changed! A Cornucopia of Antigens for Membranous Nephropathy

By Dr. Rebecca May

Jun 29, 2022

Membranous glomerulopathy is an autoimmune disease-causing nephrotic syndrome in which there is subepithelial deposition of IgG and complements along the glomerular basement membrane. Membranous glomerulopathy is the second leading cause of nephrotic syndrome in adults. Following the description of the first membranous antigen PLA2R in 2009, there has been numerous antigens described and associations with different diseases. In addition to a discussion of the individual antigens, this review article covers a description of techniques for discovery of new antigens and how these techniques have changed over time.

Quick note: This post is to be used for informational purposes only and does not constitute medical or health advice. Each person should consult their own doctor with respect to matters referenced. Arkana Laboratories assumes no liability for actions taken in reliance upon the information contained herein.