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NCAM1, Membranous Nephropathy, Lipoic Acid in NELL1-Associated Membranous Nephropathy, SARS-CoV-2, biopsy, TGFBR3, crystalline nephropathies, Renal Intratubular Casts, viral-like inclusions, Covid-19, Anti-Brush Border Antibody Disease, MGMID, renal pathology, kidney research
Podcast

How Times Have Changed! A Cornucopia of Antigens for Membranous Nephropathy

Membranous glomerulopathy is an autoimmune disease-causing nephrotic syndrome in which there is subepithelial deposition of IgG and complements along the…

By Dr. Rebecca May
NCAM1, Membranous Nephropathy, Lipoic Acid in NELL1-Associated Membranous Nephropathy, SARS-CoV-2, biopsy, TGFBR3, crystalline nephropathies, Renal Intratubular Casts, viral-like inclusions, Covid-19, Anti-Brush Border Antibody Disease, MGMID, renal pathology, kidney research
Podcast

Lipoic acid in neural epidermal growth factor-like 1-associated membranous nephropathy: More than a coincidence?

NELL1 is a recently described antigen seen in membranous glomerulopathy, which has been associated with malignancy. A recent study linked…

By Dr. Rebecca May
NCAM1, Membranous Nephropathy, Lipoic Acid in NELL1-Associated Membranous Nephropathy, SARS-CoV-2, biopsy, TGFBR3, crystalline nephropathies, Renal Intratubular Casts, viral-like inclusions, Covid-19, Anti-Brush Border Antibody Disease, MGMID, renal pathology, kidney research
Podcast

Transforming Growth Factor Beta Receptor 3 (TGFBR3)-Associated Membranous Nephropathy

Approximately half of lupus patients have kidney disease, including membranous glomerulopathy. On renal biopsy, immunofluorescence shows granular capillary loop deposits,…

By Dr. Rebecca May

NELL1
Twitter Poll

Twitter Poll (September 9, 2021)

Answer: A, NELL1 NELL1, or neural epidermal growth factor-like 1 protein is a recently identified target antigen that has been…

Membranous Glomerulopathy, PLA2R, Diagnose This, renal pathology, Arkana Laboratories
Diagnose This!

Diagnose This (August 17, 2020)

What is your diagnosis for this patient with nephrotic syndrome? …

Arkana Laboratories, renal pathology, Membranous Nephropathy
Teaching Points

Resolving Membranous Nephropathy

A 40-year-old white male presents with 3 grams/24 hr of proteinuria and swelling around his ankles. He reports that he…


Membranous Lupus Nephritis, arkana laboratories, renal pathology, kidney biopsy
Teaching Points

Membranous Lupus Nephritis

The patient is a 19-year-old female who presents with hematuria, nephrotic range proteinuria, and a creatinine of 1.2 mg/dL. She…

Membranous Glomerulopathy, Arkana Laboratories, KDIGO Connections, Renal Pathology
KDIGO Connections

KDIGO Connections: Membranous Diagnosis Algorithm

Have you seen the latest proposed KDIGO algorithm for the diagnosis and treatment of membranous glomerulopathy? Dr. Bourne brings us…

Membranous Nephropathy, renal diseases, kidney biopsy, arkana laboratories
Teaching Points

Membranous Nephropathy After Transplantation

The biopsy shows a recurrent membranous nephropathy within a transplant. Figure 1 shows “spikes” and “holes.” Figure 2 shows mild…


Disease Week, Membranous glomerulopathy, disease week, arkana laboratories
Disease Week

Disease Week: Membranous Glomerulopathy

Monday History of MG Timeline of major discoveries in membranous glomerulopathy.   Heymann nephritis was unique as a model of…

Minimal change disease, twitter poll, arkana laboratories, renal pathology, kindey biopsy
Twitter Poll

Twitter Poll (February 6, 2019)

Answer: B Minimal change disease is the most common glomerular disease associated with thymoma. Classically, the solid tumors most commonly…

By Vanessa Moreno, MD
PLA2R-Positive Membranous Glomerulonephritis, PLA2R, KDIGO Connections, Arkana Laboratories
KDIGO Connections

KDIGO Connections: PLA2R-Positive Membranous Glomerulonephritis

KDIGO has some recommendations for anti-PLA2R testing in the research setting, but do you follow anti-PLA2R levels in your patients…


Membranous Glomerulopathy, Art of Medicine
Art of Medicine

Art of Medicine: Membranous Glomerulopathy

The painting above depicts membranous glomerulopathy. A single glomerular capillary loop with confluent subepithelial and intramembranous electron dense deposits along…

KDIGO, Membranous Glomerulopathy, KDIGO Connections, renal pathology
KDIGO Connections

KDIGO Connections: Membranous Glomerulopathy

Welcome to the first post in our new series KDIGO Connections, a series in which we are asking our nephrologist…

Obesity-Related Glomerulopathy
Teaching Points

Membranous Glomerulopathy in Obesity-Related Glomerulopathy

The patient is a 57-year-old female, with a history of morbid obesity and persistent mild proteinuria (approximately 1 gm), who…