February 7, 2019
Twitter Poll (February 6, 2019)

- Published: February 7, 2019
- By: Vanessa Moreno, MD
- Tags: Malignancy, Membranous glomerulopathy, secondary, solid organ, thymoma, tumor
Answer: B
Minimal change disease is the most common glomerular disease associated with thymoma. Classically, the solid tumors most commonly associated with MN are lung, bronchus, and gastric cancers, followed by renal cell, prostate and thymoma.
Other cancers reported with MN are colorectal, pancreatic, esophageal and hepatic carcinomas.
References:
Ronco PM. Paraneoplastic glomerulopathies: New insights into an old entity. Kidney Int 56: 355–377, 1999
Bacchetta J, Juillard L, et al. Paraneoplastic glomerular diseases and malignancies. Crit Rev Oncol Hematol 70: 39–58, 2009
Lefaucheur C, Stengel B, et al. Membranous nephropathy and cancer: Epidemiologic evidence and determinants of high-risk cancer association. Kidney Int 70: 1510–1517, 2006
Jhaveri KD, Shah HH, et al. Glomerular diseases seen with cancer and chemotherapy: A narrative review. Kidney Int 84: 34–44, 2013