Search & Filter All Posts
All Articles
(16 Results)
How Times Have Changed! A Cornucopia of Antigens for Membranous Nephropathy
Membranous Nephropathy, or Membranous Glomerulopathy, is an autoimmune disease-causing nephrotic syndrome in which there is subepithelial deposition of IgG and…
Twitter Poll (November 11, 2020)
Answer: B In a recent article by Caza et al, NCAM-1 associated membranous nephropathy has been shown to be associated…
Diagnose This (August 17, 2020)
What is your diagnosis for this patient with nephrotic syndrome? …
Membranous Glomerulopathy Subtyping
The diagnosis of membranous glomerulopathy has evolved rapidly in the past 10 years since the identification of PLA2R as the…
Resolving Membranous Nephropathy
A 40-year-old white male presents with 3 grams/24 hr of proteinuria and swelling around his ankles. He reports that he…
KDIGO Connections: Membranous Diagnosis Algorithm
Have you seen the latest proposed KDIGO algorithm for the diagnosis and treatment of membranous glomerulopathy? Dr. Bourne brings us…
Membranous Nephropathy After Transplantation
The biopsy shows a recurrent membranous nephropathy within a transplant. Figure 1 shows “spikes” and “holes.” Figure 2 shows mild…
Disease Week: Membranous Glomerulopathy
Monday History of MG Timeline of major discoveries in membranous glomerulopathy. Heymann nephritis was unique as a model of…
KDIGO Connections: PLA2R-Positive Membranous Glomerulonephritis
KDIGO has some recommendations for anti-PLA2R testing in the research setting, but do you follow anti-PLA2R levels in your patients…
Art of Medicine: Membranous Glomerulopathy
The painting above depicts membranous glomerulopathy. A single glomerular capillary loop with confluent subepithelial and intramembranous electron dense deposits along…
KDIGO Connections: Membranous Glomerulopathy
Welcome to the first post in our new series KDIGO Connections, a series in which we are asking our nephrologist…
Interstitial Foam Cells
This 52-year-old female underwent a renal biopsy as part of the workup for nephrotic syndrome. The biopsy is diagnostic for…
PLA2R Tutorial
The diagnosis of membranous glomerulopathy has been transformed in the past 10 years with the discovery of PLA2R. PLA2R is…
Twitter Poll (February 14, 2018)
ANSWER: B 10-15% of cases with renal biopsy findings consistent with PMN (positive PLA2R staining) can have negative PLA2RAb serology…
Twitter Poll (December 14, 2017)
ANSWER: C Phospholipase A2 receptor 1 (PLA2R1) is present in podocytes and proximal tubules and has been detected in ~70%…