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Twitter Poll (November 11, 2020)

By Joel Murphy, MD

Nov 12, 2020

NCAM-1, NCAM-1 associated membranous nephropathy, PLA2R, Twitter Poll, Arkana Laboratories

Answer: B

In a recent article by Caza et al, NCAM-1 associated membranous nephropathy has been shown to be associated with systemic lupus erythematosus. Clinically, the article showed that the cases had a female predominance and were seen in younger patients than that typically seen in PLA2R or THSD7A-associated membranous nephropathy. In their cohort, NCAM-1-associated membranous made up approximately 7% of all membranous lupus nephritis cases (see reference).



Caza T, Hassen S, Kuperman M, et al (in press). Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis. Kid Int (2020) DOI:



Quick note: This post is to be used for informational purposes only and does not constitute medical or health advice. Each person should consult their own doctor with respect to matters referenced. Arkana Laboratories assumes no liability for actions taken in reliance upon the information contained herein.