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Collidescope Ep. 1 | What Happens when IgA Nephropathy and Fibrillary Glomerulopathy Collide?
What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…
Diagnose This (March 28, 2022)
This is the biopsy of a patient with a mechanical heart valve and acute kidney injury, requiring hemodialysis. What is…
Glomerular Disease in Temporal Association to SARS-CoV-2 Vaccination – A Series of 29 Cases
The association of rare autoimmune responses to vaccination is well known. This study investigates the effect of COVID-19 vaccination on…
IgA Nephropathy
What is IgA nephropathy? IgA nephropathyis one of the most common causes of kidney disease. In IgA nephropathy, an abnormal…
Twitter Poll (April 9, 2020)
ANSWER: C In one of the largest cases series by Ambruz et al., IgA nephropathy (IgAN) was the most common…
Disease Week: Bacterial infection-associated glomerulonephritis and endocarditis-associated glomerulonephritis
Monday Renal disease related to infective endocarditis was first reported over 100 years ago. However, the initial literature describing nephritis…
Art of Medicine: IgA Nephropathy
The above painting shows glomeruli with mesangial hypercellularity, endocapillary hypercellularity, and crescent formation. These findings can be seen in IgA…
Twitter Poll (May 22, 2019)
ANSWER: C By the Oxford Classification of IgA nephropathy, the findings present are classified as “M1 E1 S1 T1 C0”…
Crescentic IgA nephropathy
Focal crescentic IgA nephropathy The patient is a 17-year-old white female who presents with 2.85 grams/24 hr proteinuria, microscopic hematuria,…
Disease Week: Renal Manifestations of Inflammatory Bowel Disease (IBD)
Monday Extraintestinal manifestations of inflammatory bowel disease are common and involve nearly every organ system. Renal and urinary involvement has…
Twitter Poll (April 3, 2019)
ANSWER: C IgAN is the most frequent diagnosis seen in kidney biopsies from patients with renal failure and history of…
KDIGO Connections: Secondary IgA Nephropathy
Learn about secondary IgA nephropathy. IgA depositions has been associated with many conditions including infections, cirrhosis, and others.
KDIGO Connections: Crescentic IgA Nephropathy
How do you treat Crescentic IgA Nephropathy? Learn how to define which stage the patient is in and what treatments…
IgA nephropathy with something extra…
The biopsy is from a 61-year-old man with a history of intermittent microscopic hematuria for many years who presents with…
DNAJB9 helps uncover dual pathology…
This case illustrates the utility of immunohistochemical staining for DNAJB9, a recently described biomarker for fibrillary glomerulopathy (see reference). The…