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Pediatric Nephrotic Syndrome, childhood nephrotic syndrome, CSA, CNI, juxtaglomerular apparatus
Teaching Points

Chronic Cyclosporine Toxicity in Pediatric Nephrotic Syndrome

This biopsy is from a 9-year-old boy who developed pediatric nephrotic syndrome in the first year of life and has…

Membranous Glomerulopathy Subtyping, Arkana Laboratories, Renal Pathology Teaching Points
Teaching Points

Membranous Glomerulopathy Subtyping

The diagnosis of membranous glomerulopathy has evolved rapidly in the past 10 years since the identification of PLA2R as the…

Endocarditis-Associated Glomerulonephritis, arkana laboratories, renal pathology teaching points
Teaching Points

Endocarditis-Associated Glomerulonephritis

The patient is a 45-year-old IV drug user who presents with fevers, chills, hematuria, and fatigue. On laboratory testing, he…

ALECT2 Amyloidosis, arkana laboratories, renal pathology
Teaching Points

ALECT2 Amyloidosis

The patient is a 75-year-old Hispanic male who presents with progressively worsening kidney function and a creatinine of 1.6 mg/dl…

Arkana Laboratories, renal pathology, Membranous Nephropathy
Teaching Points

Resolving Membranous Nephropathy

A 40-year-old white male presents with 3 grams/24 hr of proteinuria and swelling around his ankles. He reports that he…

Nucleated Red Blood, teaching point, arkana laboratories
Teaching Points

Nucleated Red Blood Cells in Circulation

The patient is a 70-year-old male who presents with a creatinine of 5 mg/dl and a history of primary myelofibrosis.…

HIVICK, arkana Laboratories, teaching point
Teaching Points


The patient is a 24 year-old African American male who has recently been diagnosed with HIV infection. He has not…

Methotrexate-induced acute kidney injury, Methotrexate-Induced Crystal Nephropathy, teaching points, Arkana Laboratories
Teaching Points

Methotrexate-Induced Crystal Nephropathy

The patient is a 50-year-old male who presents with a creatinine of 4.2 mg/dL (baseline 1.0 mg/dL). He has been…

BK Nephritis, renal biopsy, kidney pathology, arkana laboratories
Teaching Points

BK Nephritis

The patient is a 45-year-old male with a past medical history significant for ESKD secondary to IgA nephropathy S/P renal…

Type 1 Cryoglobulinemic Glomerulonephritis, arkana laboratories
Teaching Points

Type 1 Cryoglobulinemic Glomerulonephritis

The patient is a 75 year-old female who presents with proteinuria, a necrotic skin lesion on her lower extremity, and…

Membranous Lupus Nephritis, arkana laboratories, renal pathology, kidney biopsy
Teaching Points

Membranous Lupus Nephritis

The patient is a 19-year-old female who presents with hematuria, nephrotic range proteinuria, and a creatinine of 1.2 mg/dL. She…

Waldenström's Macroglobulinemia, arkana laboratories, teaching points for renal pathology, kidney biopsy
Teaching Points

Waldenström’s Macroglobulinemia

A 57-year-old white male presents with fatigue, mild proteinuria, and a creatinine of 1.5 mg/dL. He was diagnosed with lymphoplasmacytic…

Kappa Light Chain Cast Nephropathy, teaching point, Arkana Laboratories, renal pathology
Teaching Points

Light Chain Cast Nephropathy

A 75-year-old female is found to have a creatinine of 4.0 mg/dL on a routine laboratory examination. At the hospital,…

Membranous Nephropathy, renal diseases, kidney biopsy, arkana laboratories
Teaching Points

Membranous Nephropathy After Transplantation

The biopsy shows a recurrent membranous nephropathy within a transplant. Figure 1 shows “spikes” and “holes.” Figure 2 shows mild…

focal fibrinoid necrosis, IgA, Crescentic IgA Nephropathy, chronic kidney disease, Arkana Laboratories
Teaching Points

Crescentic IgA nephropathy

Focal crescentic IgA nephropathy The patient is a 17-year-old white female who presents with 2.85 grams/24 hr proteinuria, microscopic hematuria,…