Search & Filter All Posts



All Articles

(5 Results)
denervation (neurogenic atrophy)
Neuro Notes


This 66-year-old patient presented with complaints of asymmetric distal lower extremity weakness. Their past medical history was significant for atrial…

Succinic acid dehydrogenase (SDH) enzyme
Neuro Notes

Succinic Acid Dehydrogenase

This 60 year-old patient presented with distal asymmetric muscle weakness and normal CPK.   Which of the following abnormalities is…

target fibers

Target Fibers On Trichrome

This 40-year-old patient presented with complaints of leg cramps, lower extremity muscle weakness, and loss of muscle mass. Laboratory studies…

grouped atrophy, neuro notes, neuropathology
Neuro Notes

Grouped Atrophy

This skeletal muscle biopsy shows grouped atrophy, which is a finding characteristic of denervation. This morphologic alteration indicates the presence…

By Kelly Mrachek, MD
Exocytosis, Neuro Notes, arkana laboratories, muscle biopsy
Neuro Notes

Exocytosis in a Skeletal Muscle Biopsy

This electron micrograph of two adjacent skeletal muscle cells demonstrates simultaneous exocytosis. Exocytosis in this case shows extravasation of lysosomes…

By Kelly Mrachek, MD