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Neuro Notes
Denervation
This 66-year-old patient presented with complaints of asymmetric distal lower extremity weakness. Their past medical history was significant for atrial…
Neuro Notes
Succinic Acid Dehydrogenase
This 60 year-old patient presented with distal asymmetric muscle weakness and normal CPK. Which of the following abnormalities is…
Miscellaneous
Target Fibers On Trichrome
This 40-year-old patient presented with complaints of leg cramps, lower extremity muscle weakness, and loss of muscle mass. Laboratory studies…
Neuro Notes
Grouped Atrophy
This skeletal muscle biopsy shows grouped atrophy, which is a finding characteristic of denervation. This morphologic alteration indicates the presence…
Neuro Notes
Exocytosis in a Skeletal Muscle Biopsy
This electron micrograph of two adjacent skeletal muscle cells demonstrates simultaneous exocytosis. Exocytosis in this case shows extravasation of lysosomes…