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Diagnose This (January 31, 2022)
This is the IgG immunofluorescence from the biopsy of a 75-year-old female with AKI requiring dialysis. What is your diagnosis?…
Art of Medicine: Anti-Brush Border Antibody Disease
The above painting shows massive tubular basement membrane (electron dense on EM) deposits along proximal tubules with sparing of the…
Twitter Poll (January 16, 2019)
ANSWER: B The target of the circulating ABBA autoantibodies is LDL receptor-related protein 2 (LRP2) also known as Megalin. ABBA…
Anti-Brush Border Antibody Disease
Anti-LRP2 nephropathy is a form of kidney disease primarily affecting the elderly in which progressive renal tubular injury is seen…
Anti-Brush Border Antibody Disease IF
These photomicrographs show the classic immunofluorescence staining pattern for anti-LRP2 nephropathy, a disease that leads to severe renal tubular injury…
Diagnose This! (February 13, 2017)
Please pick the best answer. These images show characteristic findings of which of the following diseases: A) IgG4-Related Disease B)…
