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anti-brush border antibody disease
Diagnose This!

Diagnose This (January 31, 2022)

This is the IgG immunofluorescence from the biopsy of a 75-year-old female with AKI requiring dialysis. What is your diagnosis?…

Anti-Brush Border Antibody Disease
Art of Medicine

Art of Medicine: Anti-Brush Border Antibody Disease

The above painting shows massive tubular basement membrane (electron dense on EM) deposits along proximal tubules with sparing of the…


ABBA (Anti-Brush Border Antibody Disease), twitter poll, arkana laboratories, renal pathology
Twitter Poll

Twitter Poll (January 16, 2019)

ANSWER: B The target of the circulating ABBA autoantibodies is LDL receptor-related protein 2 (LRP2) also known as Megalin. ABBA…

Vanessa Moreno, MD
By Vanessa Moreno, MD
Anti-LPR2 Nephropathy
Teaching Points

Anti-Brush Border Antibody Disease

Anti-LRP2 nephropathy is a form of kidney disease primarily affecting the elderly in which progressive renal tubular injury is seen…

Teaching Points

Anti-Brush Border Antibody Disease IF

These photomicrographs show the classic immunofluorescence staining pattern for anti-LRP2 nephropathy, a disease that leads to severe renal tubular injury…


Anti-Brush Border Antibody Tubulointerstitial Nephritis
Diagnose This!

Diagnose This! (February 13, 2017)

Please pick the best answer. These images show characteristic findings of which of the following diseases: A) IgG4-Related Disease B)…

L. Nich Cossey, MD
By L. Nich Cossey, MD