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Art of Medicine: Anti-Brush Border Antibody Disease
The above painting shows massive tubular basement membrane (electron dense on EM) deposits along proximal tubules with sparing of the…
Chronic Uric Acid Nephropathy
Chronic uric acid nephropathy results from deposition within the renal parenchyma of monosodium urate monohydrate. While the disease may occur…
Granulomatous Interstitial Nephritis Differential
This biopsy is from a 25-year-old African American female with renal failure. The photomicrographs here show renal involvement by non-caseating…
IgG4-Related Tubulointerstitial Nephritis
IgG4-related disease is a systemic inflammatory and sclerosing disorder which may affect a wide range of different organs including the…
Armanni-Ebstein Lesion
Armanni-Ebstein lesion, originally described by Luciano Armanni in 1872, is characterized by vacuolization and PAS-positive glycogen accumulation within the cytoplasm…
Brush Border
Do you know how the proximal tubule brush border is related to the Nobel Prize in Chemistry? Normal proximal tubules…
Pushing Glass (September 20, 2017)
The patient is a 65-year-old African American female who presents with a protein/creatinine ratio of 2 and a serum creatinine…
Chronic Active Tubulointerstitial Nephritis
Chronic tubulointerstitial nephritis in children may be secondary to a number of possible etiologies such as drug and other exogenous…
Chronic Active Tubulointerstitial Nephritis
39 y/o male presents with acute kidney injury, creatinine 3.5 mg/dl. Bland urinalysis, serologic studies negative. Immunofluorescence study of the…
