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Teaching Points

HIV-Related Kidney Disease: HIVAN

This biopsy is taken from a patient with HIV/AIDS who presented with an elevated serum creatinine and nephrotic range proteinuria.…

Lithium-Induced Nephropathy, kidney disease, arkana laboratories, acute renal disease
Pushing Glass

Pushing Glass (May 11, 2018)

These images are from the kidney biopsy of a 45-year-old man with a history of hypertension and bipolar disease presenting…

By Md Shahrier Amin, MD
Microcystic Tubular Dilatation
Teaching Points

Microcystic Tubular Dilatation

Microcystic dilatation of tubules is a non-specific morphologic finding associated with various diseases, including obstructive nephropathy, HIV-associated nephropathy (HIVAN), congenital…


Congenital Nephrotic Syndrome
Teaching Points

Congenital Nephrotic Syndrome

The biopsy from this 5-year-old male with nephrotic syndrome shows immature glomeruli without segmental glomerulosclerosis (Fig 1), associated with focal…

APOL1 risk alleles, IgA and APOL1-Associated Nephropathy
Teaching Points

IgA and APOL1

The presence of two APOL1 risk alleles, which predominantly affects population of recent African ancestry, confers up to 29x increased…