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(28 Results)![ANCA Antibodies](https://www.arkanalabs.com/wp-content/uploads/2018/07/Twitter-Poll-July-18-2018-1-432x288.jpg)
Twitter Poll (July 18, 2018)
ANSWER: 20-30% In a case series by Boils et al. which included 49 patients with GN due to IE, 28%…
![Chronic Lesions of ANCA - Fibrous Crescent](https://www.arkanalabs.com/wp-content/uploads/Fibrous-crescent-432x288.jpg)
Chronic Lesions of ANCA – Fibrous Crescents
Fibrous crescents can be differentiated from ischemic obsolescent glomeruli based on the pattern of global sclerosis. The fibrous crescent has…
![ANCA Disease, LECT2 Amyloid, IgG4-Related Disease, AL amyloidosis, ANCA, digging deeper, Dr. Messias, Arkana Laboratories, pathology diseases](https://www.arkanalabs.com/wp-content/uploads/DiggingDeeper-432x288.jpg)
Digging Deeper, Literally
This biopsy came from a 79-year-old patient. He had presented with acute renal failure. His serum creatinine was up to…
![Arteritis](https://www.arkanalabs.com/wp-content/uploads/Chronic-ANCA-associated-arteritis-432x288.jpg)
Chronic Lesions of ANCA – Arteritis
The renal biopsy shown here is from a patient with a remote history of ANCA-associated vasculitis. The artery present in…
![ANCA Disease, LECT2 Amyloid, IgG4-Related Disease, AL amyloidosis, ANCA, digging deeper, Dr. Messias, Arkana Laboratories, pathology diseases](https://www.arkanalabs.com/wp-content/uploads/DiggingDeeper-432x288.jpg)
Hidden Treasures
This biopsy came to us due to acute renal failure and proteinuria. The patient was a gentleman in his late…
![ANCA-Associated GN](https://www.arkanalabs.com/wp-content/uploads/tp02.21-432x288.jpg)
Twitter Poll (February 21, 2018)
ANSWER: D ANCA-associated GN and anti-GBM GN are the most common causes of pulmonary-renal syndrome accounting for about 90% of…
![Approximately 25-30% of the patients with anti-GBM crescentic glomerulonephritis are ANCA positive](https://www.arkanalabs.com/wp-content/uploads/tp02.01-432x288.jpg)
Twitter Poll (February 1, 2018)
ANSWER: C Approximately 25-30% of the patients with anti-GBM crescentic glomerulonephritis are ANCA positive, usually for MPO-ANCA.
![Levamisole/Cocaine DAV](https://www.arkanalabs.com/wp-content/uploads/tp12.6-1-432x288.jpg)
Twitter Poll (December 6, 2017)
ANSWER: A Dual positivity for MPO and PR3 antibodies is a strong clue for levamisole/cocaine DAV.
![endocarditis associated glomerulonephritis](https://www.arkanalabs.com/wp-content/uploads/12-5289-05-432x288.jpg)
Endocarditis
Crescentic glomerulonephritis is most commonly an autoimmune-related glomerulonephritis (e.g. ANCA, anti-GBM disease, lupus nephritis). However, a recent case series (reference…
![Medullary Angiitis in renal biopsy](https://www.arkanalabs.com/wp-content/uploads/Fig-1-copy-6-432x288.jpg)
Renal Medullary Angiitis
This 56-year-old female presented with acute kidney injury, hematuria, and mild proteinuria. All serologic studies were negative except for antineutrophil…
![Medullary Angiitis](https://www.arkanalabs.com/wp-content/uploads/medullary-angitis-1-432x288.jpg)
Medullary Angiitis
The attached photomicrographs show the classic histopathology of renal medullary angiitis, a lesion involving the vasa recta of the medulla.…
![Necrotizing Vasculitis](https://www.arkanalabs.com/wp-content/uploads/Necrotizing-Vasculits-with-Silver-Methanamine-Massons-Trichrome-stain-copy-432x288.jpg)
Necrotizing Vasculitis
Necrotizing Vasculitis as seen with Silver Methenamine Massons Trichrome (SMMT) stain on a renal biopsy. The immunofluorescence panel was negative…
![Necrotizing Vasculitis](https://www.arkanalabs.com/wp-content/uploads/Necrotizing-vasculitis-as-shown-using-fluorescence-on-an-HE-stained-section-2-432x288.jpg)
Necrotizing Vasculitis
Necrotizing vasculitis as shown using fluorescence with DAPI-FITC-Texas Red excitation on an H&E stained section. Subtle and not so subtle…