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Necrotizing Vasculitis

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD

Apr 14, 2017

Necrotizing Vasculitis
Camera information: Calibration= 1.000 Pixels per pixel; Capture format= 1392 x 1040, Full Frame HQ; Gamma= 0.99; Gain= 1.2 x; Exposure= 240.0 ms; Auto exposure= Off; Image type= Colour; Shading= (None); Sharpening= Off; Black clip= 0; White clip= 255; Microscope information:

Necrotizing vasculitis as shown using fluorescence with DAPI-FITC-Texas Red excitation on an H&E stained section. Subtle and not so subtle necrotizing areas are seen easily using this fluorescence technique. The section shows necrotizing vasculitis in an 87-year-old male who presented with hematuria, proteinuria and a creatinine of 2.5 mg/dl. Following the biopsy, ANCA serologies were ordered with cANCA positivity.

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