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nodular glomerulosclerosis
Diagnose This!

Diagnose This! (March 5, 2018)

What is the most likely diagnosis? For bonus points, what is the basic differential for this morphologic finding (non-immune and…

By L. Nich Cossey, MD
Collagenofibrotic Glomerulopathy
Diagnose This!

Diagnose This! (February 12, 2018)

What is your diagnosis? (Congo red is negative as is routine immunofluorescence)   …

By L. Nich Cossey, MD
Membranous Glomerulopathy
By L. Nich Cossey, MD

extensive mesangial and subendothelial deposition of PAS-positive
Teaching Points

Fibronectin Glomerulopathy

A renal biopsy was performed in a 32-year-old female with microscopic hematuria and nephrotic range proteinuria of 4 grams per…

Collapsing Glomerulopathy
By L. Nich Cossey, MD
Focal Segmental Glomerulosclerosis
Teaching Points

Foot Process Effacement and Focal Segmental Glomerulosclerosis

Knowing whether a patient has clinical nephrotic syndrome and knowing the degree of podocyte foot process effacement can be helpful…


Congenital Nephrotic Syndrome
Teaching Points

Congenital Nephrotic Syndrome

The biopsy from this 5-year-old male with nephrotic syndrome shows immature glomeruli without segmental glomerulosclerosis (Fig 1), associated with focal…