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Membranoproliferative Glomerulonephritis
Teaching Points

Membranoproliferative Glomerulonephritis Pattern

This glomerulus shows a membranoproliferative glomerulonephritis (MPGN) pattern of injury. To a large extent, the etiologic differential diagnosis depends on…

nodular glomerulosclerosis
Diagnose This!

Diagnose This! (March 5, 2018)

What is the most likely diagnosis? For bonus points, what is the basic differential for this morphologic finding (non-immune and…

By L. Nich Cossey, MD
Collagenofibrotic Glomerulopathy
Diagnose This!

Diagnose This! (February 12, 2018)

What is your diagnosis? (Congo red is negative as is routine immunofluorescence)   …

By L. Nich Cossey, MD

Membranous Glomerulopathy
By L. Nich Cossey, MD
extensive mesangial and subendothelial deposition of PAS-positive
Teaching Points

Fibronectin Glomerulopathy

A renal biopsy was performed in a 32-year-old female with microscopic hematuria and nephrotic range proteinuria of 4 grams per…

Collapsing Glomerulopathy
By L. Nich Cossey, MD

Focal Segmental Glomerulosclerosis
Teaching Points

Foot Process Effacement and Focal Segmental Glomerulosclerosis

Knowing whether a patient has clinical nephrotic syndrome and knowing the degree of podocyte foot process effacement can be helpful…

Congenital Nephrotic Syndrome
Teaching Points

Congenital Nephrotic Syndrome

The biopsy from this 5-year-old male with nephrotic syndrome shows immature glomeruli without segmental glomerulosclerosis (Fig 1), associated with focal…