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Twitter Poll (March 14, 2018)
ANSWER: D FSGS secondary to adaptive changes usually present with glomerular hypertrophy (glomerulomegaly), perihilar distribution of sclerosis with hyaline deposits,…
Light Chain Proximal Tubulopathy Amyloid Proximal Tubulopathy Type
The two most common morphologic variants of light chain proximal tubulopathy (LCPT) are LCPT with and without crystal formation. Two…
Twitter Poll (February 14, 2018)
ANSWER: B 10-15% of cases with renal biopsy findings consistent with PMN (positive PLA2R staining) can have negative PLA2RAb serology…
Diagnose This! (February 12, 2018)
What is your diagnosis? (Congo red is negative as is routine immunofluorescence) …
Fibronectin Glomerulopathy
A renal biopsy was performed in a 32-year-old female with microscopic hematuria and nephrotic range proteinuria of 4 grams per…
Glomerulomegaly
This biopsy was performed on a 26 year old muscular male with history of persistent subnephrotic proteinuria (UPCR = 2.3…
Pushing Glass (January 26, 2018)
An otherwise asymptomatic 65-year-old man presents for medical evaluation after 15 years of not seeing a physician. He was noted…
Light Chain Proximal Tubulopathy with Crystals
The two most common morphologic variants of light chain proximal tubulopathy (LCPT) are LCPT with and without crystal formation. The…
Fibrinogen Aα-chain Amyloidosis
A 65-year-old male, with no significant past medical history, presents with proteinuria and worsening renal function. The serum creatinine is…
Pushing Glass (January 12, 2018)
A 70-year-old female presents with 8 grams of proteinuria and a creatinine of 2.1. She relays that she has noticed…
Diagnose This! (January 8, 2018)
The immunofluorescence image shown is of IgA. What is the most likely diagnosis and clinical history? …
Antibody-Mediated Rejection
This biopsy was performed on a 37-year-old female with a history of type 1 diabetes mellitus, status post second deceased…
Twitter Poll (December 20, 2017)
ANSWER: D Immunotactoid glomerulopathy presents with Congo red-negative microtubular deposits with electron-lucent lumens measuring >30 nm in diameter.