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Exocytosis in a Skeletal Muscle Biopsy
This electron micrograph of two adjacent skeletal muscle cells demonstrates simultaneous exocytosis. Exocytosis in this case shows extravasation of lysosomes…
Sarcoidosis in a Skeletal Muscle Biopsy
These images show skeletal muscle from the thigh of an African-American patient with muscle weakness and elevated CPK levels. Occasional…
Lipid Storage Myopathy
This adult patient presented with progressive muscle weakness, elevated CK, and was admitted for rhabdomyolysis. Skeletal muscle biopsy was performed…
Diffuse Astrocytoma IDH-Mutant
The field of neuropathology is currently in a state of exponential growth and increased understanding of the pathogenesis of brain…
Pituitary Gland
Using the Wilder’s reticulin special silver stains, can you spot which image shows pathologic change in this endoscopic transnasal transsphenoidal…
Diabetic Polyneuropathy
This is an interesting common vascular finding in a sural nerve biopsy taken from an adult diabetic patient with paresthesias.…
Perifascicular Atrophy in Dermatomyositis
Perifascicular Atrophy in Dermatomyositis This case shows an acquired inflammatory myopathy with well-developed perifascicular atrophy. Generally speaking, acquired inflammatory myopathies…
New Neuropathology Series: Neuro Notes
Introducing Neuro Notes!???? This new series by our neuropathologists, Dr. Wilson and Dr. Mrachek, will be highlighting cases, diagnosing…