Back to Blog

Diagnose This (June 25, 2018)

L. Nich Cossey, MD
By L. Nich Cossey, MD

Jun 25, 2018

Membranous Glomerulopathy
Camera information: Calibration= 1.000 Pixels per pixel; Capture format= 1392 x 1040, Full Frame HQ; Gamma= 0.65; Gain= 3.0 x; Exposure= 338.9 ms; Auto exposure= Off; Image type= Colour; Shading= (None); Sharpening= Off; Black clip= 10; White clip= 212; Microscope information:

What immunofluorescence stain is shown here, what is the immune complex deposition pattern and what disease does it represent?

  ​   ​ ​   ​   ​ ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​ ​   ​ ​   ​ ​   ​ ​     ​

  ​   ​ ​   ​   ​ ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​   ​ ​  

This photomicrograph is showing a granular, capillary wall deposition pattern that is global. This pattern of deposition is most frequently seen on IgG stain in the setting of membranous glomerulopathy which is the diagnosis here.

Tags:

Quick note: This post is to be used for informational purposes only and does not constitute medical or health advice. Each person should consult their own doctor with respect to matters referenced. Arkana Laboratories assumes no liability for actions taken in reliance upon the information contained herein.