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June 25, 2018

Diagnose This (June 25, 2018)

What immunofluorescence stain is shown here, what is the immune complex deposition pattern and what disease does it represent?

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This photomicrograph is showing a granular, capillary wall deposition pattern that is global. This pattern of deposition is most frequently seen on IgG stain in the setting of membranous glomerulopathy which is the diagnosis here.