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Resolving Membranous Nephropathy
A 40-year-old white male presents with 3 grams/24 hr of proteinuria and swelling around his ankles. He reports that he…
Type 1 Cryoglobulinemic Glomerulonephritis
The patient is a 75 year-old female who presents with proteinuria, a necrotic skin lesion on her lower extremity, and…
KDIGO Connections: Membranous Glomerulopathy
Welcome to the first post in our new series KDIGO Connections, a series in which we are asking our nephrologist…
Infection-Associated Glomerulonephritis
This biopsy is taken from a 39-year-old woman who presents with abdominal pain, ascites, and lower extremity edema. Her serum…
Pushing Glass (September 7, 2018)
The patient is a 75-year-old female who presents with proteinuria and a creatinine of 2.50. She has chronic lymphocytic leukemia,…
Diagnose This! (August 6, 2018)
What is your diagnosis? This is a complicated case. The photomicrographs show a membranoproliferative pattern glomerulonephritis (MPGN) with IgG Lambda…
Diabetic Glomerulosclerosis with Superimposed Diseases
Diabetic glomerulosclerosis is one of the most common causes of nephrotic range proteinuria in adults. When the clinical course of…
Diagnose This (June 25, 2018)
What immunofluorescence stain is shown here, what is the immune complex deposition pattern and what disease does it represent? …
Membranous with FSGS
Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions. The glomerulus in this biopsy image, for…
Diagnose This (March 26, 2018)
In the setting of weak C3 (1-2+) only staining by routine immunofluorescence, what is your diagnosis? …
Vascular Staining in Membranous
This immunofluorescence (IF) image shows extensive granular glomerular capillary wall IgG deposits, consistent with membranous glomerulopathy. The glomerular staining pattern…
Pushing Glass (August 8, 2017)
A 69-year-old man with past medical history of hypertension presents with nephrotic syndrome and 7 gm/day proteinuria. Serological studies are…
