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Membranous with FSGS

T. David Bourne, MD renal pathologist and neuropathologist at arkana laboratories
By David Bourne, MD

Jun 06, 2018

Membranous with FSGS

Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions. The glomerulus in this biopsy image, for example, shows a prominent area of segmental sclerosis surrounded by mildly thickened capillary loops which have granular IgG deposits by immunofluorescence (see inset). As in other renal diseases, studies have linked the presence of FSGS lesions in patients with membranous glomerulopathy to more severe disease (e.g. higher levels of proteinuria).


Dumoulin A, Hill GS, Montseny JJ, Meyrier A. Clinical and morphological prognostic factors in membranous nephropathy: significance of focal segmental glomerulosclerosis. Am J Kidney Dis. 2003 Jan;41(1):38-48. PMID: 12500220.


Quick note: This post is to be used for informational purposes only and does not constitute medical or health advice. Each person should consult their own doctor with respect to matters referenced. Arkana Laboratories assumes no liability for actions taken in reliance upon the information contained herein.