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AA Amyloidosis, glomerular crescent
Renal Review

Case 1: A Focal Segmental Mystery

Clinical presentation: A 13-year-old male with no significant medical history presents with sudden onset nephrotic syndrome. His blood pressure is…

By Odia Molen, MD
Nephrotic Syndrome, Arkana Laboratories, renal pathology, kidney injury
By L. Nich Cossey, MD
Focal Segmental Glomerulosclerosis (FSGS)
Teaching Points

Focal Segmental Glomerulosclerosis (FSGS), Tip Variant

This biopsy was performed on a 9-year-old female with no significant past medical history, who presents with nephrotic syndrome. The…


Teaching Points

Membranous with FSGS

Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions. The glomerulus in this biopsy image, for…

Focal segmental glomerulosclerosis (FSGS)
Teaching Points

FSGS Types

Are there clues to help distinguish among primary, genetic, and secondary focal segmental glomerulosclerosis (FSGS) lesions? Focal segmental glomerulosclerosis (FSGS)…

FSGS Secondary
Twitter Poll

Twitter Poll (March 14, 2018)

ANSWER: D FSGS secondary to adaptive changes usually present with glomerular hypertrophy (glomerulomegaly), perihilar distribution of sclerosis with hyaline deposits,…

By Vanessa Moreno, MD

Focal Segmental Glomerulosclerosis
Teaching Points

Foot Process Effacement and Focal Segmental Glomerulosclerosis

Knowing whether a patient has clinical nephrotic syndrome and knowing the degree of podocyte foot process effacement can be helpful…

FSGS, focal segmental glomerulosclerosis
Teaching Points

Focal Segmental Glomerulosclerosis Not Otherwise Specified

Focal segmental glomerulosclerosis (FSGS) is a nonspecific pattern of glomerular scarring in which a subset of the glomeruli show partial…

Renal Cell Carcinoma
Teaching Points

Renal Cell Carcinoma and Adjacent Kidney

A patient with nephrotic-range proteinuria and declining renal function underwent total nephrectomy for a conventional clear cell renal cell carcinoma…