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AA Amyloidosis, glomerular crescent
Renal Review

Case 1: A Focal Segmental Mystery

Clinical presentation:A 13-year-old male with no significant medical history presents with sudden onset nephrotic syndrome. His blood pressure is 160/90. …

Focal and Segmental Glomerulosclerosis
Diagnose This!

Diagnose This (February 7, 2022)

In a patient with subnephrotic proteinuria, negative immunofluorescence, and segmental foot process effacement, what is your diagnosis?​ ​   ​…

Patient Resources

Focal Segmental Glomerulosclerosis (FSGS)

What is focal segmental glomerulosclerosis (FSGS)? Focal segmental glomerulosclerosis (commonly abbreviated as FSGS) is a kidney disease. It is one of…


Nail-Patella syndrome, Twitter Poll, Arkana Laboratories
Twitter Poll

Twitter Poll (August 5, 2020)

Answer: A, Autosomal recessive inheritanceNail-Patella syndrome is a rare autosomal dominant disease with an incidence of approximately 1/50,000. The majority…

Nail-Patella syndrome, Twitter Poll, Arkana Laboratories
Twitter Poll

Twitter Poll (August 5, 2020)

 ANSWER: A, Autosomal RecessiveNail-Patella syndrome is a rare autosomal dominant disease with an incidence of approximately 1/50,000. The majority of…

Nephrotic Syndrome, Arkana Laboratories, renal pathology, kidney injury
Diagnose This!

Diagnose This (March 25, 2019)

What is your diagnosis?​ ​   ​   ​ ​   ​   ​   ​   ​   ​…

By L. Nich Cossey, MD

Membranous with FSGS
Teaching Points

Membranous with FSGS

Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions. The glomerulus in this biopsy image, for…

Fabry disease
Diagnose This!

Diagnose This (April 23, 2018)

What is your diagnosis?  ​   ​ ​   ​   ​ ​   ​   ​   ​  …

By L. Nich Cossey, MD
Focal segmental glomerulosclerosis (FSGS)
Teaching Points

FSGS Types

The 3 main FSGS TypesAre there clues to help distinguish among primary, genetic, and secondary focal segmental glomerulosclerosis (FSGS) lesions?Focal…


secondary focal segmental glomerulosclerosis
Diagnose This!

Diagnose This (April 16, 2018)

The immunofluorescence study is negative. What is your diagnosis?​   ​ ​   ​   ​ ​   ​  …

By L. Nich Cossey, MD
Sickle Cell Nephropathy
Twitter Poll

Twitter Poll (March 28, 2018)

ANSWER: DSome of the histologic features observed in Sickle Cell Nephropathy that involve the glomerular compartment are: enlarged glomeruli with…

By Vanessa Moreno, MD
FSGS Secondary
Twitter Poll

Twitter Poll (March 14, 2018)

ANSWER: DFSGS secondary to adaptive changes usually present with glomerular hypertrophy (glomerulomegaly), perihilar distribution of sclerosis with hyaline deposits, and…

By Vanessa Moreno, MD

Podcast

MCD and FSGS

This week, Dr. Silva discusses minimal change disease, FSGS, and the controversy surrounding these two, potentially linked diseases. 

Fred Silva, MD renal pathologist at arkana laboratories
By Dr. Fred Silva
Focal Segmental Glomerulosclerosis
Teaching Points

Foot Process Effacement and Focal Segmental Glomerulosclerosis

Knowing whether a patient has clinical nephrotic syndrome and knowing the degree of podocyte foot process effacement can be helpful…

FSGS, focal segmental glomerulosclerosis
Teaching Points

Focal Segmental Glomerulosclerosis Not Otherwise Specified

Focal segmental glomerulosclerosis (FSGS) is a nonspecific pattern of glomerular scarring in which a subset of the glomeruli show partial…