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Focal and Segmental Glomerulosclerosis
Diagnose This!

Diagnose This (February 7, 2022)

In a patient with subnephrotic proteinuria, negative immunofluorescence, and segmental foot process effacement, what is your diagnosis? …

Nail-Patella syndrome, Twitter Poll, Arkana Laboratories
Twitter Poll

Twitter Poll (August 5, 2020)

Answer: A, Autosomal recessive inheritance Nail-Patella syndrome is a rare autosomal dominant disease with an incidence of approximately 1/50,000. The…

Nail-Patella syndrome, Twitter Poll, Arkana Laboratories
Twitter Poll

Twitter Poll (August 5, 2020)

  ANSWER: A, Autosomal Recessive Nail-Patella syndrome is a rare autosomal dominant disease with an incidence of approximately 1/50,000. The…


Nephrotic Syndrome, Arkana Laboratories, renal pathology, kidney injury
L. Nich Cossey, MD
By L. Nich Cossey, MD
Teaching Points

Membranous with FSGS

Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions. The glomerulus in this biopsy image, for…

Fabry disease
L. Nich Cossey, MD
By L. Nich Cossey, MD

Focal segmental glomerulosclerosis (FSGS)
Teaching Points

FSGS Types

Are there clues to help distinguish among primary, genetic, and secondary focal segmental glomerulosclerosis (FSGS) lesions? Focal segmental glomerulosclerosis (FSGS)…

secondary focal segmental glomerulosclerosis
Diagnose This!

Diagnose This (April 16, 2018)

The immunofluorescence study is negative. What is your diagnosis? …

L. Nich Cossey, MD
By L. Nich Cossey, MD
Sickle Cell Nephropathy
Twitter Poll

Twitter Poll (March 28, 2018)

ANSWER: D Some of the histologic features observed in Sickle Cell Nephropathy that involve the glomerular compartment are: enlarged glomeruli…

Vanessa Moreno, MD
By Vanessa Moreno, MD

FSGS Secondary
Twitter Poll

Twitter Poll (March 14, 2018)

ANSWER: D FSGS secondary to adaptive changes usually present with glomerular hypertrophy (glomerulomegaly), perihilar distribution of sclerosis with hyaline deposits,…

Vanessa Moreno, MD
By Vanessa Moreno, MD
Podcast

MCD and FSGS

This week, Dr. Silva discusses minimal change disease, FSGS, and the controversy surrounding these two, potentially linked diseases.

Fred Silva, MD renal pathologist at arkana laboratories
By Dr. Fred Silva
Focal Segmental Glomerulosclerosis
Teaching Points

Foot Process Effacement and Focal Segmental Glomerulosclerosis

Knowing whether a patient has clinical nephrotic syndrome and knowing the degree of podocyte foot process effacement can be helpful…


FSGS, focal segmental glomerulosclerosis
Teaching Points

Focal Segmental Glomerulosclerosis Not Otherwise Specified

Focal segmental glomerulosclerosis (FSGS) is a nonspecific pattern of glomerular scarring in which a subset of the glomeruli show partial…

FSGS Tip Lesion
Teaching Points

FSGS Tip Lesion – Secondary

The patient is a 64-year-old male with a history of diabetes mellitus, hypertension, and hyperlipidemia, who presents with an increased…

FSGS Tip Lesion
Teaching Points

FSGS Tip Lesion

This biopsy is from a 35-year-old male with no significant medical history, who presents with sudden onset nephrotic syndrome. At…