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Case 1: A Focal Segmental Mystery
Clinical presentation: A 13-year-old male with no significant medical history presents with sudden onset nephrotic syndrome. His blood pressure is…
Diagnose This (February 7, 2022)
In a patient with subnephrotic proteinuria, negative immunofluorescence, and segmental foot process effacement, what is your diagnosis? …
Twitter Poll (August 5, 2020)
Answer: A, Autosomal recessive inheritance Nail-Patella syndrome is a rare autosomal dominant disease with an incidence of approximately 1/50,000. The…
Twitter Poll (August 5, 2020)
ANSWER: A, Autosomal Recessive Nail-Patella syndrome is a rare autosomal dominant disease with an incidence of approximately 1/50,000. The…
Membranous with FSGS
Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions. The glomerulus in this biopsy image, for…
FSGS Types
Are there clues to help distinguish among primary, genetic, and secondary focal segmental glomerulosclerosis (FSGS) lesions? Focal segmental glomerulosclerosis (FSGS)…
Diagnose This (April 16, 2018)
The immunofluorescence study is negative. What is your diagnosis? …
Twitter Poll (March 28, 2018)
ANSWER: D Some of the histologic features observed in Sickle Cell Nephropathy that involve the glomerular compartment are: enlarged glomeruli…
Twitter Poll (March 14, 2018)
ANSWER: D FSGS secondary to adaptive changes usually present with glomerular hypertrophy (glomerulomegaly), perihilar distribution of sclerosis with hyaline deposits,…
MCD and FSGS
This week, Dr. Silva discusses minimal change disease, FSGS, and the controversy surrounding these two, potentially linked diseases.
Foot Process Effacement and Focal Segmental Glomerulosclerosis
Knowing whether a patient has clinical nephrotic syndrome and knowing the degree of podocyte foot process effacement can be helpful…
Focal Segmental Glomerulosclerosis Not Otherwise Specified
Focal segmental glomerulosclerosis (FSGS) is a nonspecific pattern of glomerular scarring in which a subset of the glomeruli show partial…
FSGS Tip Lesion – Secondary
The patient is a 64-year-old male with a history of diabetes mellitus, hypertension, and hyperlipidemia, who presents with an increased…
