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August 24, 2021

Glomerular Basement Membranes

Glomerular Basement Membranes, Subepithelial deposits
This eyeSCANdy image shows an acellular scanning EM of glomerular basement membranes from a biopsy with membranous glomerulonephritis, stage II showing a reticular pattern of the subepithelial GBM. The extracted deposits previously resided in the dark spaces. The lighter GBM corresponds to “spikes” on silver stain.
 
Photo credits to Dr. Stephen Bonsib.