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Diagnose This (December 6, 2021)
Which underlying systemic disease does this patient most likely have? …
Target Fibers On Trichrome
This 40-year-old patient presented with complaints of leg cramps, lower extremity muscle weakness, and loss of muscle mass. Laboratory studies…
First Friday Pizza Party
Aint no party like a pizza party! First Fridaylunch from American Pie Pizzahas to be one of the best ones…
Theoretical Impact Of The AT(N) Framework On Dementia Using A Community Autopsy Sample
The AT(N) research framework categorizes eight biomarker profiles using amyloid (A), tauopathy (T), and neurodegeneration (N), regardless of dementia status.
Development And External Validation Of A Diagnostic Model For Biopsy-Proven Acute Interstitial Nephritis Using Electronic Health Record Data
Patients with acute interstitial nephritis (AIN) can present without typical clinical features, leading to a delay in diagnosis and treatment.…
Increasing Incidence Of Inadequate Kidney Biopsy Samples Over Time: A 16-Year Retrospective Analysis From A Large National Renal Biopsy Laboratory
Recently, there has been a perceived change in the number of inadequate samples. The aim of this study was to…
Christmas Vacation
River is supposed to be helping out our IT team, but it looks like hes already checked out and ready…
Diagnose This (November 29, 2021)
What is your differential diagnosis for this ultrastructural finding? …
Membranous Glomerulonephritis
This eyeSCANdy image of acellular scanning EM shows craters at high power on the subepithelial aspect of the glomerular basement…
It’s Beginning To Look A Lot Like Christmas
HO HO HO It may be the day after Thanksgiving, but we are already in the Christmas spirit!
How Times Have Changed! A Cornucopia Of Antigens For Membranous Nephropathy
The identification of the major target antigen phospholipase A2 receptor (PLA2R) in the majority of primary (idiopathic) cases of membranous…
Resistant Starch Slows the Progression of CKD in the 5/6 Nephrectomy Mouse Model
In patients with chronic kidney disease, toxins normally excreted by the kidney continue to circulate, leading to increased kidney damage.…
Arcane Apoptosis In Appendicitis: Clue To Covid-19 In Children Or Coincidence?
We had observed increased apoptosis in two appendixes in children who developed acute appendicitis after COVID-19 infection. We wondered if…
Diagnose This (November 22, 2021)
In a non-diabetic patient, with positive IgG, kappa and lambda staining by immunofluorescence, what is your diagnosis? …
Glomerular Basement Membrane Duplication
This eyeSCANdy acellular scanning EM image of a glomerular basement membrane shows duplication in a biopsy with membranoproliferative pattern of…