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June 21, 2018

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While the majority of cryoglobulinemic GN’s do not show ultrastructural organization in deposits by EM, classically described deposits are subendothelial/intramembranous and composed of organized microtubular structures (10-30 nm wide). They can show “fingerprinting” patterns and can also be seen within intraluminal thrombi in glomerular capillaries.