Back to Blog

Acute Pyelonephritis

T. David Bourne, MD renal pathologist and neuropathologist at arkana laboratories
By David Bourne, MD

Jul 19, 2017

Acute Pyelonephritis, arkana laboratories, renal biopsy, renal disease

The renal biopsy image shows features characteristic of acute pyelonephritis. There is a neutrophil-rich interstitial inflammatory infiltrate and evidence of acute tubular injury. Some tubular lumens are filled with neutrophils (arrow), and in some areas, neutrophils encircle the outer aspect of the tubules between the tubular basement membrane and the interstitium (arrowhead). In some cases, micro abscesses may even form (not shown). In most cases of ascending infection, large vessels and glomeruli are uninvolved. If arteritis or neutrophilic infiltrates involve glomeruli, the possibility of a hematogenous infectious source should be considered.


Quick note: This post is to be used for informational purposes only and does not constitute medical or health advice. Each person should consult their own doctor with respect to matters referenced. Arkana Laboratories assumes no liability for actions taken in reliance upon the information contained herein.