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antibody-mediated rejection, arkana laboratories, renal pathology, diagnose this, kidney disease
Diagnose This!

Diagnose This (January 12, 2021)

What are the two major changes seen in this image from an allograft kidney and what are these findings concerning…

IgA, IgA Dominant Infection-Associated Glomerulonephritis, renal pathology, arkana laboratories, pathology of the kidney
Diagnose This!

Diagnose This (December 10, 2018)

What is your diagnosis?       The images show a necrotizing, crescentic, and endocapillary proliferative glomerulonephritis with IgA deposition…

By L. Nich Cossey, MD
Infection-Associated Glomerulonephritis in renal biopsy
Teaching Points

Infection-Associated Glomerulonephritis

This biopsy is taken from a 39-year-old woman who presents with abdominal pain, ascites, and lower extremity edema. Her serum…


Infection-Associated Glomerulonephritis
Diagnose This!

Diagnose This (April 2, 2018)

What is the most likely diagnosis? …

By L. Nich Cossey, MD
Acute Pyelonephritis
Teaching Points

Acute Pyelonephritis in Transplants

Acute pyelonephritis in transplant settings (allograft pyelonephritis) is a known cause of allograft dysfunction and a complication that occurs in…

renal vein thrombosis
Teaching Points

Renal Vein Obstruction

This biopsy is from a 60-year-old female, status post renal transplant 5 days prior, who was found to have mechanical…


Acute Post-Infectious Glomerulonephritis
Teaching Points

Acute Post-Infectious Glomerulonephritis

These renal biopsy images are from an 8-year-old boy who experienced the abrupt onset of hypertension, lower extremity edema, gross…

Acute Pyelonephritis
Teaching Points

Acute Pyelonephritis

This renal biopsy from a 65-year-old male with a history of E. Coli urinary tract infection and bacteremia shows severe…

Chronic Active Tubulointerstitial Nephritis
Teaching Points

Chronic Active Tubulointerstitial Nephritis

Chronic tubulointerstitial nephritis in children may be secondary to a number of possible etiologies such as drug and other exogenous…


Infection-associated glomerulonephritis
By L. Nich Cossey, MD
Acute Pyelonephritis, arkana laboratories, renal biopsy, renal disease
Teaching Points

Acute Pyelonephritis

The renal biopsy image shows features characteristic of acute pyelonephritis. There is a neutrophil-rich interstitial inflammatory infiltrate and evidence of…

Medullary Angiitis in renal biopsy
Teaching Points

Renal Medullary Angiitis

This 56-year-old female presented with acute kidney injury, hematuria, and mild proteinuria. All serologic studies were negative except for antineutrophil…


Medullary Angiitis
Teaching Points

Medullary Angiitis

The attached photomicrographs show the classic histopathology of renal medullary angiitis, a lesion involving the vasa recta of the medulla.…