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twitter poll, calcium oxalate, renal pathology, arkana laboratories
Twitter Poll

Twitter Poll (November 25, 2020)

Answer: B Ethylene glycol toxicity due to oral ingestion classically shows acute tubular injury characterized by epithelial simplification, loss of…

Unresolved etiologies, Throwback Thursday, Dr. Fred Silva, Arkana Laboratories

Unresolved Etiologies: When the Clinical Acumen Takes Place

Dr. Silva comments on several diagnostic dilemmas where the pathology pattern leads to a plethora of possibilities.

Fred Silva, MD renal pathologist at arkana laboratories
By Dr. Fred Silva
KDIGO Connections

KDIGO Connections: Contrast Induced AKI

Management guidelines and “contrasting” opinion regarding contrast-associated acute kidney injury (AKI).  

renal hemosiderosis, arkana laboratories, teaching point, renal pathology
Teaching Points


An 80-year-old white male presents with a creatinine of 4.2 (baseline 1.1) on routine lab examination. His medical history is…

kappa light chain, diagnose this, arkana laboratories, renal pathology
By L. Nich Cossey, MD
Renal oxalosis, arkana laboratories, teaching point at arkana Laboratories, renal pathology
Teaching Points

Renal Oxalosis

A 25-year-old female presents to the hospital with malaise and a creatinine of 3.5. She reports that she was in…

ANCA Disease, LECT2 Amyloid, IgG4-Related Disease, AL amyloidosis, ANCA, digging deeper, Dr. Messias, Arkana Laboratories, pathology diseases
Digging Deeper

Step By Step

The biopsy is from a 65 year-old female who presented with acute renal failure and elevated creatinine up to 1.9…

By Nidia Messias, MD
Rhabdomyolysis in kidney biopsy at Arkana Laboratories
Diagnose This!

Diagnose This (November 19, 2018)

What is your diagnosis? What additional stains would you like to confirm your diagnosis? …

By L. Nich Cossey, MD
Hall's stain, bile casts
Twitter Poll

Twitter Poll (September 26, 2018)

ANSWER: D Halls stain is used to confirm the presence of bile casts. This technique uses the oxidizing action of…

By Vanessa Moreno, MD

Acute Tubular Necrosis
Diagnose This!

Diagnose This (July 16, 2018)

What is your diagnosis in this native kidney biopsy? And for bonus points, what do you suspect is the underlying…

By L. Nich Cossey, MD
Intravascular Hemolysis
Teaching Points

Hemoglobin Casts

This 58-year-old African American male without significant past medical history presents with fatigue and weakness. During workup, he was found…

stained calcium deposits
Teaching Points

Bile Stained Calcium Oxalate Crystals

A renal biopsy was performed on this 75-year-old female who presented with acute liver failure, jaundice and acute renal failure…

Myoglobin Casts
By L. Nich Cossey, MD
Teaching Points

Oxalate Due to Vitamin C

  A 51-year-old female with a history of SLE was found to have acute renal failure. There was no evidence…

Nephrocalcinosis in Sarcoid, renal cortex
Teaching Points

Nephrocalcinosis in Sarcoid

The renal biopsy in these photomicrographs shows tubular injury with increased interstitial calcium phosphate deposition. Focal interstitial calcium phosphate can…