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Art of Medicine: Diabetic Nephropathy
The above painting shows glomeruli with nodular mesangial expansion and arterial hyalinosis, changes frequently seen in diabetic nephropathy. Diabetic nephropathy…
Dual Glomerulopathies
In this episode, Dr. Silva discusses the historical and current thinking on dual glomerulopathies, what the literature reports, and how…
IgA Dominant Infection-Associated Glomerulonephritis
A 65-year-old male presents to the ER with a new onset rash and blood in his urine. The ER doc…
Not Quite Nodular
This biopsy came from a 70-year-old gentleman with acute renal failure. He had a known history of diabetes, hypertension, and…
Diabetic Glomerulosclerosis with Superimposed Diseases
Diabetic glomerulosclerosis is one of the most common causes of nephrotic range proteinuria in adults. When the clinical course of…
Interstitial Eosinophils
Prominent interstitial eosinophils (see arrow) are most often associated with allergic-type acute interstitial nephritis (AIN). However, interstitial eosinophils are not…
Diagnose This! (March 5, 2018)
What is the most likely diagnosis? For bonus points, what is the basic differential for this morphologic finding (non-immune and…
Diabetic Nephropathy
Protein Insudative Lesions in Diabetic Glomerulopathy Diffuse and nodular glomerulosclerosis is the classic appearance of diabetic glomerulopathy. However, diabetic nephropathy…
FSGS Tip Lesion – Secondary
The patient is a 64-year-old male with a history of diabetes mellitus, hypertension, and hyperlipidemia, who presents with an increased…
IgG Background Staining in Diabetic Nephropathy
Immunofluorescence staining with IgG in a patient with diabetic nephropathy shows enhanced linear staining along the glomerular basement membranes and…
Eosinophil-Rich Inflammation in Diabetic Glomerulopathy
These photomicrographs are from a patient with diabetic nephropathy as evidenced by the Kimmelstiel-Wilson nodules in the glomerulus present on…
Diffuse and Nodular Glomerulosclerosis in Diabetic Glomerulopathy
Diffuse and nodular glomerulosclerosis is the classic appearance of diabetic glomerulopathy. Note the variability in mesangial areas in this one…